Presence of human papillomavirus DNA in testicular biopsies from nonobstructive azoospermic men.

Context: Human papillomavirus (HPV) plays a major role in the etiology of many malignancies of diverse localization, such as uterine cervical carcinoma and its precursors. Human papillomavirus sequences have been detected throughout the male lower genitourinary tract, but the role of men as transmitters remains unclear.

Objective: To investigate the relationship between azoospermia and the presence of HPV DNA in testicular cells.