Oral toxicity of the acetone extract of Coffea arabica var. Oro Azteca leaves in CD-1 mice.

The investigation of coffee leaves as a source of bioactive principles represents a relatively unexplored area of research. The study assesses the potential adverse effects of an aqueous acetone extract derived from Coffea arabica var. Oro Azteca leaves.

The Synergistic Effect of Quince Fruit and Probiotics ( and ) on Reducing Oxidative Stress and Inflammation at the Intestinal Level and Improving Athletic Performance during Endurance Exercise.

Endurance exercise promotes damage at the intestinal level and generates a variety of symptoms related to oxidative stress processes, inflammatory processes, microbiota dysbiosis, and intestinal barrier damage. This study evaluated the effects of quince ( Mill.) and probiotics of the genera and on intestinal protection and exercise endurance in an animal swimming model.

Preeclampsia association of placental nucleotide variations in eNOS, VEGFA, and FLT-1 genes in Latin American pregnant women.

Introduction: Preeclampsia is a leading cause of maternal and fetal morbidity in low- and middle-income countries, including those in Latin America. Placental vascular alterations are crucial in the pathophysiology of preeclampsia and few studies have evaluated nucleotide variations on genes associated with vascular regulation in the human placenta. This study aimed to evaluate whether placental nucleotide variations on eNOS, VEGFA, and FLT-1 genes are more frequently associated with preeclampsia in the Latin American population.

Influence of Genetic Admixture Components on Allele-Associated Hypertension in Amerindian Populations From Northwest Mexico.

metabolizes endogenous substrates and ~30% of prescription drugs. The gene contains an active allele, and a non-functional version, the (rs776746), with consequences for drug therapeutic responses and side effects. Both and have been associated with hypertension.