Publications by authors named "Alejandro Posadas-Nava"
sFlt-1 Is an Independent Predictor of Adverse Maternal Outcomes in Women With SARS-CoV-2 Infection and Hypertensive Disorders of Pregnancy.
Jose Antonio Hernandez-Pacheco Johnatan Torres-Torres Raigam Jafet Martinez-Portilla Juan Mario Solis-Paredes Guadalupe Estrada-Gutierrez Alejandro Posadas-Nava
Front Med (Lausanne)
May 2022
Article Synopsis
- The study investigates the link between sFlt-1 levels and adverse maternal outcomes in pregnant women with COVID-19, specifically focusing on those with and without hypertensive disorders.
- The researchers conducted a multicenter retrospective cohort study with 148 pregnant women, using statistical methods to analyze the data and identify key predictors of adverse outcomes.
- Results indicate that higher sFlt-1 levels and the presence of hypertensive disorders significantly increase the risk of adverse outcomes, highlighting sFlt-1 as an independent predictor regardless of hypertension status.
Background And Objective: The use of fibrinogen concentrate to treat or prevent major bleeding with regard to potential adverse reactions has not been free of controversy. Our objective was to perform a post-authorization safety study to describe the use of Clottafact (LFB Biomedicaments) fibrinogen concentrate in real-life medical practice in Mexico.
Methods: This was a prospective, observational study that collected and evaluated information between January 2017 and June 2019 related to suspected serious adverse reactions (SUSARs) during and after Clottafact infusion.