Publications by authors named "Alejandro Mesples"
Article Synopsis
- The study evaluated the safety and effectiveness of autologous bone marrow stem cell (ABMSC) transplantation in 6 children aged 6-10 with newly diagnosed autoimmune diabetes.
- The treatment involved stimulating bone marrow with Filgrastim, harvesting mononuclear cells, and transplanting them without prior immunoablation.
- Results showed a significant reduction in islet cell antibodies, decreased blood sugar levels, and no complications during the follow-up period.
Background: Bone marrow stem cell treatment has been proven a promising therapeutic strategy and showed significant results given the strong immune modulating properties. We have investigated the safety and efficacy of autologous bone marrow stem cell transplantation through liver puncture in two patients with recently diagnosed type 1 diabetes mellitus.
Material And Methods: The procedure was approved by the Institutional Ethics Committee.