Improvements in Injection Moulds Cooling and Manufacturing Efficiency Achieved by Wire Arc Additive Manufacturing Using Conformal Cooling Concept.

The plastic injection moulding industry is a constantly developing industrial field. This industrial process requires the manufacturing of metal moulds using complex heating and cooling systems. The purpose of this research is to optimize both the plastic injection moulding process and the mould manufacturing process itself by combining practices in this industry with current additive manufacturing technologies, specifically Wire Arc Additive Manufacturing (WAAM) technology.

Analysis of Energy and Material Consumption for the Manufacturing of an Aeronautical Tooling: An Experimental Comparison between Pure Machining and Big Area Additive Manufacturing.

Additive manufacturing (AM) has been fully incorporated into both the academic and the industrial world. This technology has been shown to lower costs and environmental impacts. Moreover, AM-based technologies, such as wire arc additive manufacturing (WAAM), have been proven suitable for the manufacturing of large products with significant mechanical requirements.

Efficacy and safety of rituximab in the treatment of non-renal systemic lupus erythematosus: a systematic review.

Objective: To analyse the efficacy and safety of rituximab in the treatment of non-renal systemic lupus erythematosus (SLE).

Methods: We systematically searched MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials up to June 2013. The following were the selection criteria: (1) adult patients with SLE, (2) rituximab treatment, (3) placebo or active comparator, (4) outcome measures assessing efficacy and/or (5) safety.