Corrigendum to "WCN24-319 EFFICACY OF THERAPY WITH DOUBLE PLASMA MOLECULAR ADSORPTION SYSTEM IN SEVERE ACUTE LIVER INJURY SECONDARY TO CYTOMEGALOVIRUS: CASE REPORT" [ Volume 9, Issue 4, Supplement, April 2024, Page S523-S524].

[This corrects the article DOI: 10.1016/j.ekir.

Insecticidal, antifeedant and acetylcholinesterase inhibitory activity of sesquiterpenoids derived from eudesmane, their molecular docking and QSAR.

This work evaluated the insecticidal, antifeedant and AChE inhibitory activity of compounds with eudesmane skeleton. The insecticidal activity was tested against larvae of Drosophila melanogaster and Cydia pomonella, the compounds 3 and 4 were the most active (LC of 104.2 and 106.

Effect of the Onset of Intramammary Infection on the Electrical Conductivity of Ewe's Milk and Study of Various Algorithms for Its On-Line Detection.

The aim of this study was to determine the effect of the onset of intramammary infection (IMI) on the electrical conductivity (EC) of ewe milk and assess the detection capability of various algorithms based on daily glandular milk EC measurement. An experiment was carried out with 26 Manchega sheep located at the farm of the Miguel Hernández University, Elche, Spain. The variables in milk from the gland (production, EC) were monitored daily for 2 weeks during the morning and evening milking; once infection was established in the gland, the variables were measured for a further 4 weeks.

Application of multi-target positioning algorithm in basketball teaching system and injury prevention.

In today's era, the rapid spread of information and the rise of major network platforms provide good conditions for online learning and at the same time provide a new development idea for basketball teaching. The establishment of modern multimedia teaching theory provides theoretical support for the research and development of this subject. Construct and apply the online learning system of basketball basic technology, provide high-quality education, and can accommodate a large number of basketball fans to study and exchange together, and improve the physical fitness of young people.

Constructing an architecture-based cybersecurity solution for a system.

Cybersecurity can be effectively managed with an architecture-based approach, composed with three viewpoints, namely system, security and process. Using models for describing a system and its security objectives enables a systemic and exhaustive risk management process. The architecture approach produces an integral set of security policies and controls that can be fully maintained during the entire system life-cycle.

Optimal Parameters to Milk Murciano-Granadina Goats in Mid and Low-Line Milking Parlours.

Recent short-term studies on Murciano-Granadina goats have established that the optimal parameters to set up the milking machines are different according to the milk pipes height. Two groups of 52 fresh goats each were employed in 2 different experiments to confirm during an entire lactation period the best combinations of system vacuum pulsation rate and pulsator ratio in low-line and mid-line milking parlours. The experiment performed in the low-line milking parlour included one group milked with 40 KPa vacuum system level, 90 puls/min pulsation rate and 60/40 pulsation and a second group milked with 38 KPa vacuum system level, 90 puls/min pulsation rate and 60/40 pulsation ratio.

Reticulocyte mitochondrial retention increases reactive oxygen species and oxygen consumption in mouse models of sickle cell disease and phlebotomy-induced anemia.

Sickle cell disease (SCD) is caused by a mutation of the β-globin gene that results in the production of hemoglobin S (HbS). People with SCD experience anemia, severe acute pain episodes, persistent chronic pain, multiorgan damage, and a reduced life span. The pathophysiology of SCD caused by the polymerization of HbS on deoxygenation results in red cell deformability and the generation of reactive oxygen species (ROS).

Sleep Quality as a Predictor of Quality-of-Life and Emotional Status Impairment in Patients with Chronic Spontaneous Urticaria: A Cross-Sectional Study.

Chronic Spontaneous Urticaria (CSU) leads to a decreased quality of life in patients because of pruritus and skin lesions. However, there is still little evidence on the impact that a worse sleep quality could have on the quality of life and emotional disorders in these patients. The aims of the present study are to analyze the potential impact of sleep quality on the quality-of-life and emotional status of patients with CSU.

Effect of Vacuum Level and Pulsation Parameters on Milking Efficiency and Animal Welfare of Murciano-Granadina Goats Milked in Mid-Line and Low-Line Milking Machines.

The Murciano-Granadina goat breed has been described as a slow milking breed. As milking machine parameters can affect milk extraction in terms of yield and time employed, two experiments of one-month duration were performed with 88 goats in Latin square design to find the best combination of these parameters. One of them was carried out in a mid-line milking machine and one in a low-line milking machine.

N95 vs Half-face Respirator Wear in Surgical Trainees: Physiologic and Psychological Effects of Prolonged Use.

Objectives: As specialists of the upper airway, otolaryngologists are at high risk for COVID-19 transmission. N95 and half-face respirator (HFR) masks are commonly worn, each with advantages in functionality and comfort. In this study, physiologic and psychological parameters of prolonged N95 vs HFR wear were compared.

Temporal and spatial analysis of benomyl/carbendazim in water and its possible impact on Nile tilapia (Oreochromis niloticus) from Tenango dam, Puebla, Mexico.

Activities like agriculture contribute to the pollution of aquatic systems by fungicides, such as benomyl/carbendazim. This chemical inhibits the activity of acetylcholinesterase (AChE), having teratogenic, oncogenic, reproductive, and hepatic effects on aquatic and soil organisms. This paper presents the results of a study conducted in the Tenango dam, Mexico, aimed at detecting and determining the spatial and temporal variability of benomyl/carbendazim fungicide in the dam's water and its possible impact on Nile tilapia (Oreochromis niloticus), farmed and commercialized in the site.

Family and social environment associated with traits of antisocial personality disorder in the prison population of Peru.

Introduction: The prison environment in Peru is one of the worst in the continent. In situations such as these, where there is considerable stress, many inmates can develop antisocial disorders, especially if they come from a conflictive family setting.

Objectives: To determine the association between family relationships, social environment and features of antisocial personality disorder (ASPD) in the Peruvian prison population in 2016.

Automatic Prestimulation on Dairy Goats: Milking Efficiency and Teat-End Status.

Experiments carried out in dairy cows show that mechanical stimulation prior to milking offers a good release of oxytocin without involving changes in milk yield or a reduction of the milking time. The objective of the present study was to evaluate the effect of automatic prestimulation on milk fractioning, milking duration and milk flows, teat-end status, and vacuum levels at the short milk tubes and in the pulsation tubes of dairy goats. With this aim, three experiments in Latin square design were developed employing goats in different moments of the lactation: one of them at the onset of lactation, one at mid-lactation, and the last at the end of lactation.

Alcoholic-Hepatitis, Links to Brain and Microbiome: Mechanisms, Clinical and Experimental Research.

The following review article presents clinical and experimental features of alcohol-induced liver disease (ALD). Basic aspects of alcohol metabolism leading to the development of liver hepatotoxicity are discussed. ALD includes fatty liver, acute alcoholic hepatitis with or without liver failure, alcoholic steatohepatitis (ASH) leading to fibrosis and cirrhosis, and hepatocellular cancer (HCC).

De novo EIF2AK1 and EIF2AK2 Variants Are Associated with Developmental Delay, Leukoencephalopathy, and Neurologic Decompensation.

EIF2AK1 and EIF2AK2 encode members of the eukaryotic translation initiation factor 2 alpha kinase (EIF2AK) family that inhibits protein synthesis in response to physiologic stress conditions. EIF2AK2 is also involved in innate immune response and the regulation of signal transduction, apoptosis, cell proliferation, and differentiation. Despite these findings, human disorders associated with deleterious variants in EIF2AK1 and EIF2AK2 have not been reported.

Using the "ligamentum flavum gap" to identify originally missed type B vertebral fractures.

Background: Spine fractures may involve the ligamentum flavum (LF). Here, we utilized the "ligamentum flavum gap," defined by the discontinuity of the LF at the level of a vertebral fracture, to document a vertebral fracture.

Methods: Utilizing X-rays, computed tomography (CT), and magnetic resonance (MR) studies, 10 patients with type B vertebral fractures were diagnosed with the ligamentum flavum gap (LFG: discontinuity of the LF) at the fracture levels.

Relationship of mammary gland health status and other noninfectious factors with electrical conductivity of milk in Manchega ewes.

Measuring the electrical conductivity (EC) of milk during milking has been extensively studied in cattle as a low-cost mastitis detection method that can be easily automated. The aim of this work was to study the effect of the health status of the glands and several noninfectious factors (lactation stage, milking session, and lactation number) that affect the use of EC measurement of milk to detect mastitis in dairy sheep livestock. Likewise, we studied the relation between EC and milk composition (macrocomposition and mineral content) and between EC and somatic cell count (SCC).

[Evidence on afatinib in patients progressing on a first-line treatment].

After description of the importance of EGFR mutations in non-small cell lung cancer and confirmation that tyrosine-kinase inhibitors are more beneficial than chemotherapy in patients with EGFR+ tumours, treatment with one of these drugs has become the standard recommendation. Despite this advance, patients continue to progress and consequently there is a need to search for alternative treatments. Some studies have analysed afatinib activity after first-generation TKI therapy, as well as its administration in combination with conventional chemotherapy.

A Community-based Healthy Living Promotion Program Improved Self-esteem Among Minority Children.

Objectives: Improving self-esteem, dietary habits, and physical activity is essential for long-term success in childhood obesity prevention. The aim is to evaluate the effects of a healthy living promotion program, Healthy Kids-Houston, on BMI, dietary habits, self-esteem, and physical activity among minority children.

Methods: The after-school program was implemented at community centers in low-income neighborhoods with close proximity to public schools.

Evidence of Fasciola spp. resistance to albendazole, triclabendazole and bromofenofos in water buffaloes (Bubalus bubalis).

Fasciolosis caused by Fasciola spp. is considered the most important helminth infection of ruminants in tropical countries. Anthelmintic resistance has become a global concern.

Health care and end-of-life decisions: community engagement with adults in East Harlem.

This was a model of community engagement for a Hispanic population in East Harlem, New York City to assess health care decision-making processes, with a focus on end-of-life decisions, among older men and women. The design involved two senior center-based semi-structured focus groups conducted in Spanish and English followed by a series of bilingual skills-building workshops focusing on situational decision-making. All program aspects were conducted between April and June of 2013.

Short communication: effects of milk removal on teat tissue and recovery in Murciano-Granadina goats.

The aim of this work was to study how machine milking (MM) carried out in appropriate conditions affects teat wall thickness and canal length and their return after milking to premilking conditions compared with other milk removal methods considered biological referents: kid suckling (KS), catheter removal (CATH), and hand milking (HM). Three Latin square experiments were designed, each divided into 2 periods. In the first period, the left glands of each animal were machine milked and the KS, CATH, and HM treatments were applied to the right glands in experiments 1, 2, and 3, respectively.

How does the milk removal method affect teat tissue and teat recovery in dairy ewes?

The aim of this work was to study how machine milking (MM) carried out in suitable conditions affects teat wall thickness and teat canal length and their return after milking to pre-milking conditions, in comparison with other milk extraction methods considered biological referents: lamb suckling (LS), milk removal by catheter (RC) and hand milking (HM). Three Latin square experiments were designed, using 11 ewes in the first experiment (LS), 13 in the second (RC) and 12 in the third (HM). Each of the Latin squares was divided into two periods: in the first, the left gland of each animal was machine milked and the corresponding treatment (LS, RC and HM) was applied to the right gland.

Is active surveillance a safe alternative in the management of localized prostate cancer? Pathological features of radical prostatectomy specimens in potential candidates for active surveillance.

Introduction And Objective: Active surveillance (AS) has become an accepted alternative for patients with low risk prostate cancer. The purpose of AS is to defer definitive therapy in these patients to avoid treatment-related complications. Our aim was to determine the pathological features of the surgical specimen from potential AS candidates that underwent radical prostatectomy (RP).

Effects of overmilking and liner type and characteristics on teat tissue in small ruminants.

The aim of this work was to study the effect on teat wall thickness and canal length in sheep and goats of overmilking for 2 min (OM+2) and of milking with used (AL; +3000 milkings) and twisted (TL; 45°) liners in sheep and goats, as well as the effect of milking goats with liners designed for sheep (SL, shorter length and diameter than liners for goats). To this end, we performed four experiments in goats and three in sheep, in a Latin square design with two experimental periods. During the experimental period 4 controls were carried out, performing ultrasound scans before and immediately after milking to determine the teat wall thickness (TWT), teat wall area (TWA), teat end area (TEWA) and teat canal length (TCL).