Publications by authors named "Alejandro Ledo-Rodriguez"
An artificial intelligence-assisted system versus white light endoscopy alone for adenoma detection in individuals with Lynch syndrome (TIMELY): an international, multicentre, randomised controlled trial.
Lancet Gastroenterol Hepatol
September 2024
Background: Computer-aided detection (CADe) systems for colonoscopy have been shown to increase small polyp detection during colonoscopy in the general population. People with Lynch syndrome represent an ideal target population for CADe-assisted colonoscopy because adenomas, the primary cancer precursor lesions, are characterised by their small size and higher likelihood of showing advanced histology. We aimed to evaluate the performance of CADe-assisted colonoscopy in detecting adenomas in individuals with Lynch syndrome.
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- A study was done to see if a type of screening test called FIT was better than the usual procedure, colonoscopy, for first-degree relatives of people with colorectal cancer.
- The researchers wanted to know if more people would agree to take the FIT test compared to colonoscopy and if both tests would find the same number of serious issues.
- The study was planned to involve many people over several years but had to stop early because it wasn't looking like it would have good results, even though they still gathered data for two years after.
Sorafenib is an oral multikinase inhibitor that is useful in the treatment of various solid cancer. We report a patient who developed an acneiform facial eruption during treatment with this medication.
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