The INC has been a pioneer in producing cardiac bioprostheses in Mexico. Since the 1970's it has produced and implanted more than 2,500 bioprostheses, first made of duramater and later on, made of cattle pericardium. Nowadays, it is working on the production of a new generation of bioprostheses of cattle pericardium as well as of pigs with or without support; to these, a system to reduce calcification has been added, as a result of research being performed at the Applied Biotechnics Department.
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