International registry of dermatological manifestations secondary to COVID-19 infection in 347 Hispanic patients from 25 countries.

Background: The infection by coronavirus disease 2019 (COVID-19) has been associated with multiple cutaneous manifestations, although characterization of them in Hispanic patients with darker skin phototypes is lacking. The objective of this study is to characterize the clinical dermatological manifestations associated with COVID-19 infection in cases with few or without general symptoms in patients from Latin America.

Methods: Cross-sectional study using a questionnaire that was made for health professionals (physicians with a specialty in dermatology) to investigate dermatological lesions associated with COVID-19 infection in patients from 25 countries of Latin America.

Síndrome metabólico y aterosclerosis carotídea subclínica en niños y adolescentes mexicanos con acantosis nigricans.

IntroducciÓn: La acantosis nigricans es un marcador de resistencia a la insulina, la cual se asocia con alteraciones metabólicas y cardiovasculares.

Objetivo: Investigar la frecuencia de síndrome metabólico y aterosclerosis carotídea subclínica en niños y adolescentes mexicanos con acantosis nigricans y comparar los resultados entre sexos.

MÉtodo: Estudio transversal.

An epidermal nevus syndrome with cerebral involvement caused by a mosaic FGFR3 mutation.

A 5-year-old Mexican girl had a bilateral, systematized epidermal nevus of a non-epidermolytic, non-organoid type covering large parts of her body with the exception of the scalp. Clinically, this nevus was of a soft, velvety type showing affinity to the large body folds. Histopathological examination revealed orthohyperkeratosis and papillomatosis without granular degeneration and without any abnormality of adnexal structures.

Scalp demodicidosis mimicking favus in a 6-year-old boy.

Demodex folliculorum and Demodex brevis are obligatory ectoparasites of the pilosebaceous unit in humans. Although most people are infested with these mites, only a small number develop clinical symptoms of demodicidosis. We report a case of demodicidosis in a 6-year-old boy who had lesions on the scalp, forehead, neck, and anterior chest for 18 months.

Association of beta-defensin 1 single nucleotide polymorphisms with atopic dermatitis.

Background: Atopic dermatitis (AD) is a chronic multifactorial allergic disease with unclear etiology. The antimicrobial human beta-defensin 1 is chemotactic for dendritic cells, which are important regulators of allergic immune responses. In an attempt to identify useful markers that could predict susceptibility to AD, we investigated single nucleotide polymorphisms (SNPs) of the beta-defensin 1 gene (DEFB1) with potential functional consequences.