Publications by authors named "Alejandro Ezequiel Cristofalo"
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Synopsis of recent research by authors named "Alejandro Ezequiel Cristofalo"
- Alejandro Ezequiel Cristofalo's research focuses on the synthesis of complex carbohydrates, particularly thiodisaccharides that mimic components found in biological substances like hyaluronan and keratan.
- His notable work includes the synthesis of β--GlcA(1→3)GlcNAc and β--Gal(1→3)GlcNAc thiodisaccharides through innovative chemical reactions involving S2 displacement and vinyl azide intermediates.
- Cristofalo's findings revealed the serendipitous formation of 2,3-dideoxy-(1→2) thiodisaccharides, showcasing the versatility of the vinyl azide as a precursor in carbohydrate chemistry, and the stereochemical outcomes were confirmed using NOESY experiments.
