Publications by authors named "Alejandro Edan-Sanchez"
J Affect Disord
January 2025
Article Synopsis
- The study explores sex differences in sleep disturbances during major depressive episodes (MDE), finding that a high prevalence of sleep complaints exists for both genders, but with variations in types and associations.
- Women showed higher rates of sleep issues and specific comorbidities like histrionic personality disorder, while men were more associated with mania and substance use disorders.
- The research highlights the importance of tailored treatment approaches for men and women based on their unique profiles, despite the limitations of the cross-sectional design which doesn't establish causality.
Eur Neuropsychopharmacol
October 2023
Article Synopsis
- - A multicenter study analyzed over 59,000 COVID-19 patients to see if antipsychotics affected 28-day mortality, finding no significant link for most antipsychotics despite previous conflicting research.
- - In a matched sample of 1,454 patients, the use of antipsychotics did not show a notable difference in survival rates, with a mortality rate of 23.5% for users versus 18.6% for non-users.
- - Interestingly, higher doses of certain antipsychotics (over 200 mg of chlorpromazine-equivalents) were associated with reduced mortality, indicating that while typical doses may not worsen outcomes, higher doses might have a protective effect.
