Publications by authors named "Alejandro Cob"
Time in range and mean glucose cut-off points for reduction of fetal outcomes in pregnant women with type 1 diabetes using automated insulin delivery systems.
Diabetes Res Clin Pract
November 2024
Article Synopsis
- This study investigates how time in range (TIRp) and mean glucose levels during pregnancy impact fetal health in women with Type 1 Diabetes (T1D) using automated insulin delivery (AID) systems.* -
- The findings reveal that a TIRp below 59.1% and mean glucose over 133 mg/dL in the second trimester are linked to higher instances of fetal outcomes like large for gestational age (LGA) and hyperbilirubinemia.* -
- It suggests that improving TIRp, especially through the early use of advanced hybrid closed loop (AHCL) systems, could enhance fetal outcomes, although more research is required to solidify these recommendations.*
Aim: This study aimed to describe the prescription patterns of second-line medications for patients with diabetes from selected centers in Costa Rica and Panama.
Methods: DISCOVER is a registry of patients with type 2 diabetes switching from first- to second-line medications. We analyzed medication choice and the reasons to switch for each country.
Introduction: Anterior hypopituitarism is a common complication of head trauma, with a prevalence of 30% to 70% among long-term survivors. This is a much higher frequency than previously thought and suggests that most cases of post-traumatic hypopituitarism remain undiagnosed and untreated. Symptoms of hypopituitarism are very unspecific and very similar to those in traumatic brain injury patients in general, which makes hypopituitarism difficult to diagnose.
View Article and Find Full Text PDFAlthough there are international guidelines orienting physicians on how to manage patients with acromegaly, such guidelines should be adapted for use in distinct regions of the world. A panel of neuroendocrinologists convened in Mexico City in August of 2007 to discuss specific considerations in Latin America. Of major discussion was the laboratory evaluation of acromegaly, which requires the use of appropriate tests and the adoption of local institutional standards.
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