Intraocular pressure: Goldmann tonometry, computational model, and calibration equation.

Purpose: There exists a concern about the general accuracy of intraocular pressure (IOP) measurements using tonometry, and especially Goldmann applanation tonometer (GAT) because it considers the cornea as an infinite thin shell. In this study, the relationship between the true IOP and tonometric IOP, external curvature radius (ECR), and central corneal thickness (CCT) is explored.

Methods: In this study, the calibration of the IOP measurements through GAT for different values of CCT, ECR, and E (Young modulus), is done through computational simulations of the mechanical behavior of the cornea subjected to the applanation process using the finite element method (FEM).