Publications by authors named "Alejandra Melgarejo Ortuno"

Article Synopsis
  • Biological drugs have positively impacted the treatment outcomes for pediatric inflammatory bowel disease (IBD), making it vital to predict their effectiveness, especially in growing children.
  • There are specific clinical, biochemical, and genetic factors that may help predict responses to these drugs, but research focused on children with IBD is limited.
  • This review highlights the latest findings on biological therapies for pediatric IBD and explores various biomarkers, including demographics, clinical traits, and microbiota analysis.
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Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease that often requires biological therapy to control its activity. Medication persistence and adherence are important aspects on which we have scarce information. We performed a longitudinal, retrospective, and observational study based on data from the daily clinical management of JIA patients.

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Few large series describe the clinical characteristics, outcomes and costs of COVID-19 in Western countries. This cohort reports the first 1255 adult cases receiving anti-COVID-19 treatment at a Spanish hospital (1-24 March 2020). Treatment costs were calculated.

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Article Synopsis
  • Acute graft-versus-host disease (aGVHD) is a serious problem that can happen after bone transplant when the body fights against the new cells.
  • Steroids are usually the first treatment, but some patients don’t respond well to them.
  • In one case, doctors used a medicine called tocilizumab, and it helped the patient get better very quickly, showing it could be a good option for people who don’t improve with steroids.
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Background: The large number of available cancer apps and their impact on the population necessitates a transparent, objective, and comprehensive evaluation by app experts, health care professionals, and users. To date, there have been no analyses or classifications of apps for patients with genitourinary cancers, which are among the most prevalent types of cancer.

Objective: The objective of our study was to analyze the quality of apps for patients diagnosed with genitourinary cancers using the Mobile Application Rating Scale (MARS) and identify high-quality apps.

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Introduction: parenteral nutrition (PN) compounding is a process with a high probability of errors. Objective: to analyze PN compounding errors detected using a gravimetric control (GC) and a component verification control (CVC). Methods: a prospective analysis was carried out during a three-year period (January 2016 to December 2018).

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