Leptin/adiponectin ratio as a prognostic factor for increased weight gain in girls with central precocious puberty.

Objective: To determine if the leptin, adiponectin, and leptin/adiponectin ratio (LAR) can predict weight gain at the end of GnRH analogs (GnRHa) treatment in girls with central precocious puberty (CPP).

Material And Methods: Study design: prospective cohort. Serum levels of leptin and adiponectin were determined at diagnosis of CPP.

[Thyroid dysfunction due to 131I-metaiodobenzylguanidine in patients with neuroblastoma].

Introduction: The treatment of advanced neuroblastoma includes chemotherapy, surgery, and radiotherapy with 131-I-Metaiodobenzylguanidine (131-I-MIBG). Despite strategies to protect thyroid function, its dysfunction is reported between 12 and 85%.

Objective: To identify the frequency of thyroid dys function in cases of neuroblastoma treated with 131-I-MIBG.

The Mexican Acromegaly Registry: Clinical and Biochemical Characteristics at Diagnosis and Therapeutic Outcomes.

Context: Acromegaly is a systemic disorder caused by a GH-secreting pituitary adenoma. As with other rare diseases, acromegaly registries developed in various European countries have provided us with important information.

Objective: The objective of the study was to analyze the epidemiological, clinical, biochemical, and therapeutic data from the Mexican Acromegaly Registry (MAR).

Influence of the informal primary caretaker on glycemic control among prepubertal pediatric patients with type 1 diabetes mellitus.

Objectives: In prepubertal type 1 diabetic patients (DM1), the availability of an informal primary caregiver (ICP) is critical to making management decisions; in this study, the ICP-related risk factors associated with glycemic control were identified.

Patients, Materials, And Methods: A comparative cross-sectional study was performed. Fifty-five patients with DM1 under the age of 11 years were included.

Change in body mass index among girls with precocious puberty under treatment.

Introduction: Changes in body mass index (BMI) among girls with idiopathic central precocious puberty (ICPP) under treatment have been controversial in other populations.

Objective: To assess changes in BMI Z score and the rate of overweight and obesity in Mexican girls with ICPP during their first year of treatment.

Methodology: A retrospective study was conducted among girls with ICPP under treatment with leuprolide, with a somatometry performed every six months, over a 1-year period.

[Pediatric patients with type 1-diabetes: growth and growth failure associated factors].

Background: Type 1 diabetes (T1D) usually occurs in the pediatric age and affects the growth of children. The aim of this work was to describe growth and growth failure associated factors in a population of children with T1D in a tertiary level pediatric hospital.

Methods: A case-control nested in a cohort study was conducted.