A systematic review of the relationships between family functioning, pubertal timing and adolescent substance use.

Aims: Experiences linked to poor family functioning and pubertal timing have each been associated with increased risk of substance misuse in adolescence. However, it remains unclear to what extent family functioning and pubertal timing combine to put adolescents at particular risk.

Method: A systematic review was planned, undertaken and reported according to the 27 items of the PRISMA statement.