Sustained Release Studies of Metformin Hydrochloride Drug Using Conducting Polymer/Gelatin-Based Composite Hydrogels.

The present work highlights the synthesis and characterization of conducting polymer (CP)-based composite hydrogels with gelatin (GL-B) for their application as drug delivery vehicles. The spectral, morphological, and rheological properties of the synthesized hydrogels were explored, and morphological studies confirmed formation of an intense interpenetrating network. Rheological measurements showed variation in the flow behavior with the type of conducting polymer.

Synthesis and characterization of pH-responsive conducting polymer/Na-alginate/gelatin based composite hydrogels for sustained release of amoxicillin drug.

Composite hydrogels of Na-Alginate (Na-ALG) and Gelatin (GEL) with conducting polymers (CPs) were synthesised using poly(o-phenylenediamine) (POPD), polyaniline (PANI), poly(1-naphthylamine (PNA) and poly(vinylenedine fluoride) (PVDF). The synthesised hydrogels were characterized using FTIR, scanning electron microscopy (SEM) rheology, swelling ability and in-vitro drug release characteristics. The purpose of this investigation was to determine whether these hydrogels could be used to deliver antibiotics for extended drug release.

A short review on the synthesis and advance applications of polyaniline hydrogels.

Conductive polymeric hydrogels (CPHs) exhibit remarkable properties such as high toughness, self-recoverability, electrical conductivity, transparency, freezing resistance, stimulus responsiveness, stretch ability, self-healing, and strain sensitivity. Due to their exceptional physicochemical and physio-mechanical properties, among the widely studied CPHs, polyaniline (PANI) has been the subject of immense interest due to its stability, tunable electrical conductivity, low cost, and good biocompatibility. The current state of research on PANI hydrogel is discussed in this short review, along with the properties, preparation methods, and common characterization techniques as well as their applications in a variety of fields such as sensor and actuator manufacturing, biomedicine, and soft electronics.