Publications by authors named "Alec Winder"

Article Synopsis
  • This study examines the effectiveness of a risk calculator for predicting sentinel lymph node (SLN) positivity in patients with AJCC T1-T2 melanomas at the Melanoma Institute Australia.
  • The analysis compared SLN biopsy rates and positivity between two time periods: before and after implementing the nomogram, with findings showing increased SLN biopsy rates in lower-risk melanoma patients post-nomogram.
  • The results suggest that the SLN risk calculator significantly impacts clinical practice, particularly for T1a and higher-risk T1b melanomas, indicating a need for updated guidelines to improve patient selection for SLN biopsies.
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Background: Breast cancer has become the most frequently diagnosed cancer in the world. Detection at an early stage, frequently allows women to benefit from breast conserving surgery. However, some patients are not satisfied with the breast shape after breast-conserving surgery, and autologous tissue flaps are needed to fill the defect in the resection area.

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Background: Breast cancer patients having neoadjuvant systemic therapy (NAST) who have a positive (clipped) lymph node (CN) at presentation must have that CN removed to assess pathologic response at later surgery. Multiple techniques for localizing the CN have been described. We describe a novel ROLL-based approach.

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Background: Pathological complete response (pCR), in breast cancers, after neoadjuvant chemotherapy is linked to improved survival. Determining complete response to chemotherapy prior to surgery has remained elusive even using a combination of pathological factors and imaging modalities, making surgery still a necessity.

Methods: A retrospective analysis was performed from a single institution from 2013 to 2018.

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Background And Objectives: The aim of surgical treatment of gastrointestinal stromal tumors (GIST) is a microscopically complete resection. Initial indications for laparoscopic surgery were limited to smaller tumors, in favorable locations. Over time, indications for minimal invasive surgery (MIS) have expanded, however concerns remain when considering resection of larger GISTs.

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Obesity has been linked to an increased prevalence in multiple cancers. Studies have suggested a reduction in the overall risk of cancer after bariatric surgery. We reviewed the evidence for bariatric surgery reducing the risk of endometrial cancer.

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We reviewed the evidence for bariatric surgery reducing the risk of breast cancer. Data was extracted from multiple libraries, including PubMed, EMBASE, and Medline, to perform a systematic review. Abstracts were reviewed by two independent reviewers.

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