Publications by authors named "Alec Dallas"

In serology, each sample is typically tested individually, one antigen at a time. This is costly and time consuming. Serology techniques should ideally allow recurrent measurements in parallel in small sample volumes and be inexpensive and fast.

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Patients with small-cell lung cancer (SCLC) are in dire need of more effective therapeutic options. Frequent disruption of the G1 checkpoint in SCLC cells creates a dependency on the G2/M checkpoint to maintain genomic integrity. Indeed, in pre-clinical models, inhibiting the G2/M checkpoint kinase WEE1 shows promise in inhibiting SCLC growth.

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Article Synopsis
  • Scientists found that tumors are made up of different types of cells, which can affect how they grow and how well treatments work.
  • They created a new way to track these different cells using special tags and imaging technology, called EpicMIBI.
  • By using this technology on small cell lung cancer models, they discovered that certain cancer cells could grow faster when mixed with other types, showing how complex tumors can be.
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