Awake vs. asleep motor mapping for glioma resection: a systematic review and meta-analysis.

Background: Intraoperative stimulation (IS) mapping has become the preferred standard treatment for eloquent tumors as it permits a more accurate identification of functional areas, allowing surgeons to achieve higher extents of resection (EOR) and decrease postoperative morbidity. For lesions adjacent to the perirolandic area and descending motor tracts, mapping can be done with both awake craniotomy (AC) and under general anesthesia (GA).

Objective: We aimed to determine which anesthetic protocol-AC vs.