Publications by authors named "Aldosari H"

Creutzfeldt-Jakob disease (CJD) is a rare, rapidly progressive, and incurable neurodegenerative disorder caused by prions. It is invariably fatal and classified under transmissible spongiform encephalopathies. This case report presents a 66-year-old Saudi female who was admitted to the neurology department due to a rapidly advancing cognitive decline.

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Background And Objective: Sickle cell disease (SCD) complications, such as sickle cell nephropathy (SCN), may begin in childhood and progress insidiously to chronic kidney disease in adulthood. In Saudi Arabia (SA), there is a lack of studies evaluating kidney function in children with SCD. This study aims to assess microalbuminuria (MA) as an early marker of renal dysfunction in SCD children living in the Eastern region of SA, to potentially institute appropriate early treatment.

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Recent sensor, communication, and computing technological advancements facilitate smart grid use. The heavy reliance on developed data and communication technology increases the exposure of smart grids to cyberattacks. Existing mitigation in the electricity grid focuses on protecting primary or redundant measurements.

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This research describes the methodology for synthesizing zinc oxide nanoparticles (ZnO-NPs). It demonstrates a unique, cost-effective, and non-toxic chemical technique for producing ZnO-NPs using the precipitation method with NaOH as reducing and capping agents. The formed nanoparticles have been characterized and analyzed using numerous techniques such as; Fluorescence emission spectroscopy (FL), X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy-dispersive X-ray Spectroscopy (EDX), ultraviolet-visible optical absorption (UV-Vis), Fourier transform infrared spectroscopy (FTIR), and Thermal gravimetric analysis (TGA).

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Beckwith-Wiedemann syndrome (BWS) is a rare genomic imprinting disorder that affects multiple systems. Major features can manifest as large birth weight, anterior abdominal wall defects, macroglossia, hyperinsulinism, organomegaly hemihypertrophy, and renal abnormalities. Characteristic facies manifested as midface hypoplasia, infraorbital creases, facial nevus simplex, and anterior linear ear lobe creases/posterior helical ear pits, with a predisposition to tumor development.

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Article Synopsis
  • The study aimed to develop machine learning algorithms to analyze electrocardiograms (ECGs) for diagnosing cardiac autonomic neuropathy (CAN) in diabetic patients.
  • Researchers utilized motif and discord extraction techniques along with long short-term memory networks to evaluate the effectiveness of these methods using various performance metrics via 10-fold cross-validation.
  • The findings showed high accuracy in detecting severe CAN (dsCAN) with an accuracy of 0.92, while detecting any stage of CAN had a lower accuracy of 0.65, suggesting the potential of machine learning in improving CAN diagnosis and screening.
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Cranial epidermoid cysts are relatively rare. More frequently reported in middle-aged men with a wide variety of signs and symptoms such as headache, seizures, cerebellar and cranial nerve deficits/visual disturbance. The approach for surgical removal of the cyst depends on its size and location.

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One of the most practical and environmentally friendly ways to deal with the energy crises and global warming is to produce hydrogen as clean fuel by splitting water. The central obstacle for electrochemical water splitting is the use of expensive metal-based catalysts. For electrocatalytic hydrogen production, it is essential to fabricate an efficient catalyst for the counterpart oxygen evolution reaction (OER), which is a four-electron-transfer sluggish process.

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Phase-change materials (PCMs), which can transition reversibly between crystalline and amorphous phases, have shown great promise for next-generation memory devices due to their nonvolatility, rapid switching periods, and random-access capability. Several groups have investigated phase-change nanowires for memory applications in recent years. The ability to regulate the scale of nanostructures remains one of the most significant obstacles in nanoscience.

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Evaluating and tracking the size of a wound is a crucial step in wound assessment. The measurement of various indicators on wounds over time plays a vital role in treating and managing crucial wounds. This article introduces the concept of utilizing mobile device-captured photographs to address this challenge.

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Artificial Intelligence (AI) is a computer system that simulates intelligent human behavior. The use of AI is rapidly shifting Healthcare. Speech recognition (SR) is a type of AI physicians use to operate Electronic Health records (EHR).

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Article Synopsis
  • PDE10A regulates body movements through cyclic adenosine monophosphate signaling in the basal ganglia, with distinct mutations linked to different clinical presentations.
  • Autosomal recessive mutations in the GAF-A domain cause infantile onset chorea and developmental delays, whereas dominant mutations in the GAF-B domain lead to childhood onset chorea but with typical cognitive development.
  • In a studied family with PDE10A mutations, individuals exhibited recessive symptoms alongside a bi-allelic GAF-B mutation, indicating unique mechanisms affecting PDE10A activity and enhancing our understanding of PDE10A-related movement disorders.
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The spread of organic pollutants in water spoils the environment, and among the best-known sorbents for removing organic compounds are carbonaceous materials. Sunflower seed waste (SFSW) was employed as a green and low-cost precursor to prepare carbon nanoparticles (CNPs) via pyrolysis, followed by a ball-milling process. The CNPs were treated with a nitric-sulfuric acid mixture (1:1) at 100 °C.

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This study demonstrated the deposition of size-controlled gold (Au) nanoclusters via direct-current magnetron sputtering and inert gas condensation techniques. The impact of different source parameters, namely, sputtering discharge power, inert gas flow rate, and aggregation length on Au nanoclusters' size and yield was investigated. Au nanoclusters' size and size uniformity were confirmed via transmission electron microscopy.

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Pediatric oncology interventions involve many challenges, such as multiple hospitalizations, invasive procedures, and adverse physical and psychological treatment side effects. Treatment burden, including administration of general anesthesia, contributes to high levels of psychological distress among pediatric patients and their families. Virtual reality (VR) is a distraction method, which offers an extremely realistic and interactive virtual environment and helps reduce pain and distress by means of a head-mounted display and headphones.

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In December 2019, Wuhan, China, reported an outbreak of nSARS-CoV2 that caused viral pneumonia, COVID-19. Li Wenliang, a Chinese ophthalmologist, first communicated on Chinese social media about the existence and spread of the unknown viral pneumonia in Wuhan, China. By the end of March 2020, the virus had spread worldwide.

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This work provides useful insights into the development of HfO-based memristive systems with a p-type silicon bottom electrode that are compatible with the complementary metal-oxide-semiconductor technology. The results obtained reveal the importance of the top electrode selection to achieve unique device characteristics. The Ag/HfO/Si devices have exhibited a larger memory window and self-compliance characteristics.

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Continuous education and training play a critical role in preparing a competent pharmacy workforce to meet the healthcare needs of the public. This study aimed to evaluate the effectiveness and feasibility of implementing a structured Continuing Professional Development (CPD) training programme for pharmacists in Kuwait. Twenty-one practicing pharmacists participated in the programme.

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Background: The pharmacy profession has changed enormously in the recent decades. Pharmacist role has been expanded beyond formulating and dispensing medications to include the provision of pharmaceutical care and public health services to patients. Patient-centred care requires sustained competency through improving pharmacist's knowledge, skills, and performance.

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Big data has been applied in a variety of ways in healthcare. It can be considered as a tool for data collection. And hence, there are certain criteria needed in this tool to be of value.

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Antimicrobial computerized decision support systems (CDSS) have been developed to improve decision-making at the point of prescribing. Uptake of CDSS for antibiotic prescribing remains low, and evidence to suggest that CDSS provides a clear benefit for antimicrobial outcomes is scarce. We reviewed existing evidence on the impact of CDSS on antimicrobial prescribing.

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Medication errorsare a leading cause of deathacross many parts of the world. Several factors increase medication errors. These can be individual-related factors, such as the burden ofa heavy workload, often experiencedby nurses, or organizational-related factors, such as inadequate space for documenting and poor labeling of medication.

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Surfaces of polycrystalline α-GeTe films were studied by X-ray photoelectron spectroscopy (XPS) after different treatments in an effort to understand the effect of premetallization surface treatments on the resistance of Ni-based contacts to GeTe. UV-O is often used to remove organic contaminants after lithography and prior to metallization; therefore, UV-O treatment was used first for 10 min prior to ex situ treatments, which led to oxidation of both Ge and Te to GeO (x < 2) and TeO, respectively. Then the oxides were removed by deionized (DI) HO, (NH)S, and HCl treatments.

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Environmentally responsive gel formulation for ocular controlled delivery of carteolol hydrochloride (HCl) was developed in an attempt to improve ocular bioavailability and hence decrease its systemic absorption and side effects. The viscosity and the ability of the prepared formulations to deliver carteolol HCl in vitro and in vivo were monitored and compared with an aqueous commercial solution. The effect of polymer concentration and drug concentration on the in vitro release of carteolol HCl was examined.

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