Publications by authors named "Aldo Alberti-Navarro"
Article Synopsis
- * This study georeferenced 3414 reports of Eimeria occurrences in cattle, sheep, and goats in Mexico from 1961 to 2018, identifying twelve species affecting cattle, eleven in sheep, and eight in goats.
- * Findings show that Eimeria primarily thrives in specific climate zones during warmer months and affects younger animals, suggesting that environmental data can enhance the understanding of its spread and aid in reducing disease prevalence in Mexico.
The current study aimed to determine the anti-Eimeria efficacy of an extract of grapefruit peels (GF) and commercial naringenin (NAR) in naturally-infected lambs, as well as the influence of these flavonoids on the oxidative status during ovine coccidiosis. Pharmacokinetic profiles were also determined. Extracts were administered per os to Eimeria naturally infected growing lambs during 90 consecutive days.
View Article and Find Full Text PDFFasciola hepatica secretes proteolytic enzymes during liver invasion. The present study examined the effects of the cysteine protease inhibitor Ep-475 on sheep considering the following variables: serum levels of aspartate aminotransferase, L-lactate dehydrogenase, and gamma-glutamyltransferase, liver fluke fecundity, egg viability, parasite burden, and size. Twenty-four male sheep were randomly allocated in four groups of six animals each as follows: group A was infected with F.
View Article and Find Full Text PDFArticle Synopsis
- The study used the film in situ zymography (FIZ) technique to show that E-64 can inhibit the proteolytic activity of Fasciola hepatica in a mouse model of fasciolosis.
- It was found that a dose of 50 mg/kg/day resulted in an 87% maximum inhibition of proteolysis and increased mouse survival by an average of nearly 11 days compared to untreated mice.
- Despite its effectiveness, some residual proteolytic activity remained, indicating that other enzymes may be involved or that E-64's effects are not complete.