Salicylic acid (SA) is a bioregulator well-known for mitigating salinity damage in plants. However, no studies have examined the interaction between SA and salinity in , a species rich in bioactive molecules. Therefore, we aimed to evaluate the effect of SA application on under different salinity levels.
View Article and Find Full Text PDFThe γ-aminobutyric acid (GABA) receptors play pivotal roles in the transmission of neuronal information in the nervous system of insects, which has led these proteins to be targeted by synthetic and natural products. Here, we assessed the insecticidal potential of the essential oil of (Gardner) Sch. Bip.
View Article and Find Full Text PDFExp Appl Acarol
April 2024
The main way to avoid contact with ticks and consequently tick-borne disease is the use of synthetic repellents. The search of new repellent compounds to increase the possibilities of use in strategies controls are necessary. The present study evaluated the repellent activity of two natural terpenes carvacrol and thymol in each one two different formulation (encapsulated and nonencapsulated with yeast cell wall) against the ticks Amblyomma sculptum and Rhipicephalus sanguineus sensu lato nymphs.
View Article and Find Full Text PDFLeishmaniases are infectious-parasitic diseases that impact public health around the world. Antileishmanial drugs presented toxicity and increase in parasitic resistance. Studies with natural products show an alternative to this effect, and several metabolites have demonstrated potential in the treatment of various diseases.
View Article and Find Full Text PDFPharmaceutics
January 2024
(Gardner) Sch.Bip., known in Brazil as alecrim do campo, is a small Asteraceae family plant with a calming effect and consumed as tea.
View Article and Find Full Text PDFEssential oils (EOs) produced by aromatic plants belonging to different families, such as Asteraceae, Lamiaceae, Lauraceae, Myrtaceae, and Piperaceae, are generally suggested as potential sources of new molecules with insecticidal activity. The EOs are constituted bioactive molecules that may have to control Drosophila suzukii (Matsumura), a serious economic invasive pest of small fruits worldwide. Currently, the control strategy against D.
View Article and Find Full Text PDFBiomed Pharmacother
December 2023
Osteoarthritis (OA) is a pathology that is characterized by progressive erosion of articular cartilage. In this context, medicinal plants have become relevant tools regarding their potential role in the prevention and treatment of OA, being safe and effective. The aim of this work was investigate the therapeutic efficacy of the ethyl acetate fraction of Bixa orellana leaves (BoEA) and ellagic acid (ElAc) for the therapeutic treatment of OA induced by monosodium iodoacetate (MIA) in rats.
View Article and Find Full Text PDFChagas disease is a severe infectious and parasitic disease caused by the protozoan and considered a public health problem. Chemotherapeutics are still the main means of control and treatment of the disease, however with some limitations. As an alternative treatment, plants have been pointed out due to their proven pharmacological properties.
View Article and Find Full Text PDFVet Parasitol
December 2021
Rhipicephalus microplus, known as the cattle tick, is a cause of great economic losses for dairy cattle farming because of its high frequency of occurrence and the difficulty in controlling it. This research characterized the chemical profile and evaluated the in vitro toxicity of crude Lithraea brasiliensis extract and its isolated compound against acaricide-resistant and acaricide-susceptible R. microplus strains.
View Article and Find Full Text PDFVet Parasitol
November 2021
Rhipicephalus microplus is an important cattle tick, and resistant strains to synthetic compounds have been widespread. The combined effects of different essential oil compounds enhance biological activity and reduce selection for the development of target organism resistance. Essential oils of two different genotypes of each of Lippia sidoides and Lippia gracilis and their main components, the isomers thymol and carvacrol, have acted as acaricides against R.
View Article and Find Full Text PDFThe Rhipicephalus (Boophilus) microplus tick is the main ectoparasite of cattle in tropical and subtropical regions worldwide. Resistance to chemical acaricides has become widespread affirming the need for new drugs to tick control. Terpenes have become a promising alternative for cattle tick control, however the mechanism of action of these compounds is still controversial.
View Article and Find Full Text PDFRhipicephalus (Boophilus) microplus (Canestrini) is a problem for livestock production systems, and its control has become challenging due to the selection of tick populations resistant to synthetic chemical acaricides. The use of repellent compounds prevents contact between the arthropod parasite and the host and can, thus, contribute to increases in the efficacy of these acaricides. Carvacrol monoterpenic phenol is a possible alternative method for controlling R.
View Article and Find Full Text PDFRev Bras Parasitol Vet
May 2018
Plants respond to wounding caused by mechanical stress or herbivory by synthesizing defense proteins. There are no studies reporting the action of induced plant proteins against ticks. The aim of this study was to investigate the effect of mechanically wounded Leucaena leucocephala leaves against Rhipicephalus (Boophilus) microplus.
View Article and Find Full Text PDFVet Parasitol
April 2017
The Essential Oils (EOs) from the leaves of species Cinnamomum verum J. Presl are used in the pharmaceutical industry for their numerous biological activities. Currently, the main compound of C.
View Article and Find Full Text PDFThe goal of the present study was to evaluate the acaricidal potential of Lippia alba essential oil, citral chemotypes (LA-10 and LA-44 genotypes) and carvone chemotypes (LA-13 and LA-57 genotypes), as well as purified citral and enantiomers of carvone and limonene. Efficacy against Rhipicephalus microplus was assessed by the larval packet and the engorged female immersion tests. Citral chemotypes had greater larvicidal activity than carvone chemotypes, and this was further supported by larvicidal and adulticidal activity of purified citral with LC50 values of 7.
View Article and Find Full Text PDFEthnopharmacological Relevance: Ethnobotanical surveys are detecting an increasing frequency of exotic plant species in pharmacopeias, which has led researchers to investigate the role of such species in traditional medical systems. According to the diversification hypothesis, exotic species are included to complete pharmacopeias, i.e.
View Article and Find Full Text PDFRhipicephalus microplus is the main tick that affects cattle. Plant bioactive molecules can be used to control this ectoparasite. The aim of this study was to evaluate the in vitro efficacy of Piper tuberculatum fruit extracts obtained with different solvents on R.
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