Publications by authors named "Alderman J"

Article Synopsis
  • There is a significant risk of reinforcing existing health inequalities in AI health technologies due to biases, primarily stemming from the datasets used.
  • The STANDING Together recommendations focus on transparency in health datasets and proactive evaluation of their impacts on different population groups, informed by a comprehensive research process with over 350 global contributors.
  • The 29 recommendations are divided into guidance for documenting health datasets and strategies for using them, aiming to identify and reduce algorithmic biases while promoting awareness of the inherent limitations in all datasets.
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  • This review analyzes various mammography datasets used for AI development in breast cancer screening, focusing on their transparency, content, and accessibility.
  • A search identified 254 datasets, with only 28 being accessible; most datasets came from Europe, East Asia, and North America, raising concerns over poor demographic representation.
  • The findings highlight significant gaps in diversity within these datasets, underscoring the need for better documentation and inclusivity to enhance the effectiveness of AI technologies in breast cancer research.
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  • During the COVID-19 pandemic, AI models were developed to help with health-care resource issues, but previous studies showed that the datasets used often have limitations leading to biased outcomes.
  • A systematic review analyzed 192 healthcare datasets from MEDLINE and Google Dataset Search, focusing on metadata completeness, accessibility, and ethical considerations.
  • Results indicated significant shortfalls, including that only 48% showed the country of origin, 43% reported age, and under 25% included demographic factors like sex or race, emphasizing the need for improved data quality and transparency to avoid bias in future AI health applications.
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Artificial intelligence as a medical device is increasingly being applied to healthcare for diagnosis, risk stratification and resource allocation. However, a growing body of evidence has highlighted the risk of algorithmic bias, which may perpetuate existing health inequity. This problem arises in part because of systemic inequalities in dataset curation, unequal opportunity to participate in research and inequalities of access.

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Through online social networks (OSNs), individuals establish and maintain social connections to satisfy their need to belong. Recent research suggests that taken too far, one's need to belong can increase envy and lead to maladaptive social media behavior aligned with obsessive-compulsive disorder (OCD). This study examines the role of two personality traits, one's intrinsic need to belong and trait reactance, on feelings of envy and the self-disclosure processes that lead to OCD on social networks.

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Article Synopsis
  • The study aimed to use clustering methods on transthoracic echocardiography (TTE) and hemodynamic parameters to identify subtypes of circulatory failure in patients with acute respiratory distress syndrome (ARDS) and to see how these relate to mortality compared to traditional definitions of right ventricular dysfunction (RVD).
  • Conducted at a university hospital ICU in Birmingham, UK, the retrospective study analyzed TTE data from 801 ICU patients diagnosed with ARDS over five years, revealing four distinct cardiovascular subphenotypes with varying 90-day mortality rates.
  • The findings suggest that these subphenotypes provide a better understanding of the underlying mechanisms of circulatory failure in ARDS and indicate that class 3 (dilated RV with impaired syst
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Background: Super-utilizers of the health care system compose a small percentage of the population, yet use the most health care resources. Hotspotting addresses this issue by providing high-quality, personalized care to this population.

Purpose: This review examined how hotspotting has been defined, implemented, and measured.

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Objectives: To describe current UK clinical practice around the use of intrathecal diamorphine as analgesia for major elective laparoscopic colorectal surgery.

Design: Online self-administered survey.

Setting: Acute public hospitals in the UK (National Health Service - NHS) .

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Unsupervised clustering methods of transthoracic echocardiography variables have not been used to characterise circulatory failure mechanisms in patients with COVID-19 pneumonitis. We conducted a retrospective, single-centre cohort study in ICU patients with COVID-19 pneumonitis whose lungs were mechanically ventilated and who underwent transthoracic echocardiography between March 2020 and May 2021. We performed latent class analysis of echocardiographic and haemodynamic variables.

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Studies have shown the impact of interprofessional education (IPE) on health professions students' knowledge, skills, and attitudes and, to some extent, its impact on patient and organizational outcomes. This retrospective quasi-experimental study explored the impact of home visits by teams of interprofessional health professions students on the readmission rates of patients recently discharged from the hospital. Patients (20 in the intervention group, 20 in the control group) were in the care of one home health agency during a 7-month period.

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Interprofessional communication (IPC) is important for the inpatient oncology team due to the complexity and acuity of oncology patients. One intervention used to improve IPC is team rounding, yet few researchers have explored experiences of team members with team rounding. In this study, 12 interviews were conducted with providers from five different professions: Nursing Assistant, Registered Nurse, Pharmacist, Advanced Practice Provider, and Physician.

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Introduction: Survival from out of hospital cardiac arrest (OHCA) is lower in the UK than in several developed nations. Bystander cardiopulmonary resuscitation (CPR) is associated with increased rates of survival to hospital discharge following OHCA, prompting the introduction of several initiatives by the UK government to increase rates of bystander CPR, including the inclusion of Basic Life Support (BLS) teaching within the English national curriculum. While there is clear benefit in this, increasing evidence suggests poor retention of skills following BLS teaching.

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Objectives: To assess whether right ventricular dilation or systolic impairment is associated with mortality and/or disease severity in invasively ventilated patients with coronavirus disease 2019 acute respiratory distress syndrome.

Design: Retrospective cohort study.

Setting: Single-center U.

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In vivo models that recapitulate human erythropoiesis with persistence of circulating red blood cells (RBCs) have remained elusive. We report an immunodeficient murine model in which combined human liver and cytokine humanization confer enhanced human erythropoiesis and RBC survival in the circulation. We deleted the fumarylacetoacetate hydrolase () gene in MISTRG mice expressing several human cytokines in place of their murine counterparts.

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