Generation, Characterisation and Identification of Bioactive Peptides from Mesopelagic Fish Protein Hydrolysates Using In Silico and In Vitro Approaches.

This study generated bioactive hydrolysates using the enzyme Alcalase and autolysis from mesopelagic fish, including and . Generated hydrolysates were investigated for their bioactivities using in vitro bioassays, and bioactive peptides were identified using mass spectrometry in active hydrolysates with cyclooxygenase, dipeptidyl peptidase IV and antioxidant activities. In silico analysis was employed to rank identified peptide sequences in terms of overall bioactivity using programmes including Peptide Ranker, PrepAIP, Umami-MRNN and AntiDMPpred.

User-Configurable Timing and Navigation for UAVs.

As the use of unmanned aerial vehicles (UAVs) for industrial use increases, so are the demands for highly accurate navigation solutions, and with the high dynamics that UAVs offer, the accuracy of a measurement does not only depend on the value of the measurement, but also the accuracy of the associated timestamp. Sensor timing using dedicated hardware is the de-facto method to achieve optimal sensor performance, but the solutions available today have limited flexibility and requires much effort when changing sensors. This article presents requirements and suggestions for a highly accurate, reconfigurable sensor timing system that simplifies integration of sensor systems and navigation systems for UAVs.

Effects of dietary lipid, vitamins and minerals on total amounts and redox status of glutathione and ubiquinone in tissues of Atlantic salmon (Salmo salar): a multivariate approach.

The hypothesis of the present study was that Atlantic salmon (Salmo salar) would respond to large variations in supplementation of dietary pro- and antioxidants, and marine lipid, with adjustment of the endogenously synthesised antioxidants, glutathione (GSH) and ubiquinone (UQ). An experiment with 2(7-3) reduced factorial design (the number of cases reduced systematically from 2(7) (full design) to 2(4) (reduced design)) was conducted, where vitamins, minerals and lipid were supplemented in the diet at high and low levels. For the vitamins and minerals the high levels were chosen to be just below anticipated toxic levels and the low levels were just above the requirement (vitamin C, 30 and 1000 mg/kg; vitamin E, 70 and 430 mg/kg; Fe, 70 and 1200 mg/kg; Cu, 8 and 110 mg/kg; Mn, 12 and 200 mg/kg).

Effects of fish meal replacement with full-fat soy meal on growth and tissue fatty acid composition in Atlantic cod (Gadus morhua).

Atlantic cod of initial mean weight approximately 220 g were fed a control diet and three diets in which fish meal (FM) was replaced with increasing levels of full-fat soybean meal (FFS) supplied at 12, 24, and 36% of dry diet, for 12 weeks. There were no significant differences in final weights, but the specific growth rate (SGR) was significantly higher in fish fed the control (FFS0) diet compared to fish fed the FFS12 and FFS36 diets, and the feed conversion ratio (FCR) was significantly lower in fish fed the FFS0 diet compared to the other three treatments. The fatty acid (FA) compositions of the cod muscle and liver were highly affected by dietary treatment, and linear relationships between dietary and tissue FA concentrations were shown for some of these.

Chemical composition, mineral content and amino acid and lipid profiles in bones from various fish species.

The chemical composition, content of minerals and the profiles of amino acids and fatty acids were analyzed in fish bones from eight different species of fish. Fish bones varied significantly in chemical composition. The main difference was lipid content ranging from 23 g/kg in cod (Gadus morhua) to 509 g/kg in mackerel (Scomber scombrus).

Minor amputations on the feet after revascularization for gangrene. A consecutive series of 95 limbs.

A consecutive series of 89 patients (95 limbs) with gangrene were operated on with amputation of toes or some distal part of the foot after arterial reconstruction. 43 patients had diabetes. Healing was achieved in 81/82 feet when the reconstruction was open.

External appearance of forensic autopsy material of alcoholics.

Forensic material of alcoholics was compared with controls with regard to the height, weight, state of nutrition, stature, the ageing process and the presence of traumatic lesions. Surprisingly, it was found that alcoholic women were taller than controls. Alcoholics were significantly more often slightly undernourished, while the extremes, severe obesity or severe undernourishment, did not show any differences.

Soft tissue infections from drug abuse. A clinical and microbiological review of 145 cases.

We evaluated clinical and microbiological aspects in 145 hospitalizations of 89 intravenous drug abusers with acute soft tissue infections at the injection site. There were 58 superficial abscesses, 27 deep abscesses, 57 cellulitis with or without concomitant ulcer, 1 purulent arthritis, 1 tenosynovitis and 1 incompletely categorized abscess. The commonest location was the groin.

Fatal agricultural accidents.

During the period 1969-1988, 33 victims (30 males and 3 females) of agricultural accidents were autopsied at the University Institute of Forensic Medicine in Copenhagen. Five were under the age of 15 years. The median age was 51 years.

An investigation of the pattern of firearms fatalities before and after the introduction of new legislation in Denmark.

All firearms fatalities in East Denmark during the period 1984-1987 were examined. There were 276 cases or 3.0 per 100,000 living inhabitants.

The natural history of chondromalacia patellae. A 12-year follow-up.

A series of 45 patients with chondromalacia patellae demonstrated clinically and by arthrotomy, but without demonstrable biomechanical misalignment, was investigated retrospectively. Thirty-one of the patients had only been treated conservatively while partial chondrectomy was performed in 14. All of the patients underwent an intensive rehabilitation program.

[Metastasizing squamous cell carcinoma in patients with psoriasis treated with immunosuppressive agents].

Immunosuppressive agents are imployed increasingly frequently in treatment of nonfatal disorders. We report two cases of metastasizing squamous cell carcinoma after treatment for psoriasis with methotrexate. Additional cases must be reported, but we consider that: 1) methotrexate medication, when possible, should be withdrawn when a localized squamous cell carcinoma is diagnosed and 2) when this diagnosis is confirmed the patient should be referred for radical treatment.

[Fatal gunshot injuries in East Denmark].

All of the fatal gunshot lesions in East Denmark during the period 1984-1987 were investigated. A total of 276 cases were found corresponding to an annual frequency of approximately 3.0 per 100,000 live population.

Detection of injuries in traumatic deaths. The significance of medico-legal autopsy.

A material of 218 medico-legal autopsies on persons with traumatic injuries was analysed. All these persons had been admitted to hospital. In 75 (34%) injuries had been missed in hospital.

Injuries due to deliberate violence in areas of Denmark. V. Violence against women and children. Copenhagen Study Group.

As part of an European-South American study of deliberate violence cases of violence against women greater than or equal to 15 years of age and violence against and among children under the age of 15 years were registered at 3 Danish emergency wards and at the Institute of Forensic Medicine in Copenhagen. 352 cases of violence against women and 46 cases of violence against children were registered in the three emergency wards corresponding to rates of about 1.6/1000 per year for women, 0.

Injuries due to deliberate violence in areas of Denmark. IV. Alcohol intoxication in victims of violence. The Copenhagen Study Group.

A material of 1316 victims of deliberate violence was collected prospectively during a one year period in three Danish emergency wards covering a provincial/rural area and two metropolitan areas. The frequency of alcohol intoxication was determined. Forty-one percent of the patients were intoxicated.

Injuries due to deliberate violence in areas of Denmark. III. Lesions. The Copenhagen Study Group.

As part of a transcultural investigation of violent behavior in Denmark and South America, the lesions from accidents involving deliberate violence registered in three Danish emergency wards during a 1-year period were studied. A quantity of 2211 lesions were diagnosed in 1316 patients (953 male and 363 female patients). Sixty-five percent of the lesions were in the head/neck region, 13% in truncus, 18% in the upper extremities and 5% in the lower extremities.

Injuries due to deliberate violence in areas of Denmark. II. Victims of homicide in the Copenhagen area.

As part of a transcultural investigation of injuries due to deliberate violence in Denmark and South America, homicides in the Copenhagen area were studied for a 1-year period. Forty-five cases corresponding to a rate of approximately 2/10(5) per year were recorded. The rate seems to be increasing and the pattern changing with a higher frequency of stabbing and with an increasing frequency of high blood-alcohol concentrations in the victims.

Injuries due to deliberate violence in areas of Denmark. I. The extent of violence.

As part of a transcultural investigation of violent behavior in Denmark and South America an analysis was made during a one year period of the incidents involving deliberate violence as registered at 3 Danish emergency wards, and at the Institute of Forensic Medicine in Copenhagen. In the three emergency wards a total of 1316 victims of deliberate violence were observed corresponding to a rate of about 3.3/1000 per year in a provincial/rural district, the catchment region of Holbaek County Hospital, 5.