Ultrasound of pneumothorax in neonates: Diagnostic value of the anterior transverse plane and of mirrored ribs.

Introduction: Point-of-care lung ultrasound is increasingly used to diagnose pneumothorax efficiently and safely in neonates.

Objectives: This study aimed to evaluate the usefulness of the central and anterior transverse thoracic plane in the ultrasound diagnosis of pneumothorax, analyze the diagnostic value of the "mirrored ribs" sign, and evaluate the predictive value of the lung point location for the need of pleural drainage.

Methods: Retrospective cohort study of all newborns admitted to the neonatal intensive care unit of the Basurto University Hospital (Bilbao, Spain) due to respiratory distress and with ultrasound, with or without pneumothorax, between January 2014 and December 2020.

NMR-based newborn urine screening for optimized detection of inherited errors of metabolism.

Inborn errors of metabolism (IEMs) are rare diseases produced by the accumulation of abnormal amounts of metabolites, toxic to the newborn. When not detected on time, they can lead to irreversible physiological and psychological sequels or even demise. Metabolomics has emerged as an efficient and powerful tool for IEM detection in newborns, children, and adults with late onset.