Saline irrigated catheter ablation for pulmonary vein isolation in pigs: an experimental model.

Focal AF is amenable to radical cure by RF ablation within the PV. The primary purpose of this study was to compare lesion characteristics for irrigated versus standard ablation using three power settings for PV isolation in pigs. Secondary analyses were the comparisons of ablation time and temperature characteristics, and evaluation of short-term safety in the pig model.

[Lesions produced by radiofrequency ablation of the cavotricuspid isthmus in an experimental model].

Introduction And Objectives: Experimental studies have shown that deeper and wider lesions (up to 10 mm long or deep) can be safely created using an 8 mm or irrigated tip catheter for ablation to treat atrial flutter. However, potential damage to the tricuspid valve or inferior cava vein has not been systematically evaluated.

Patients And Method: The cavotricuspid isthmus was ablated in 26 pigs (body weight 26-52 kg), with a total of 187 radiofrequency pulses.