Publications by authors named "Alberto Mattalia"

Objective: In this study we aimed to compare patient outcomes between the use of transarterial radioembolization (TARE) and sorafenib in patients with hepatocellular carcinoma (HCC) and intrahepatic portal vein tumor thrombosis (PVTT).

Methods: A total of 65 patients with HCC and intrahepatic PVTT treated in five Italian hospitals between 2012 and 2018 were included in the analysis. Those with any previous treatment, extension of PVTT to the main portal tract and extrahepatic involvement were excluded.

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Article Synopsis
  • * The study confirmed known associations with the IL12A and IL12RB genes.
  • * A combined analysis with Canadian data identified new risk loci at SPIB, IRF5-TNPO3, and 17q12-21, showing significant statistical associations and odds ratios indicating increased risk.
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