Publications by authors named "Alberto Massarotti"
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Synopsis of recent research by authors named "Alberto Massarotti"
- Alberto Massarotti’s recent research primarily focuses on identifying novel compounds that target various pathways involved in tumor immune evasion, notably emphasizing the dual inhibition of enzymatic and nonenzymatic functions of indoleamine 2,3-dioxygenase 1 (IDO1).
- His studies also explore therapeutic strategies that manipulate cyclic AMP (cAMP) signaling in pulmonary cells through targeted non-natural peptides aimed at enhancing lung function and alleviating inflammation.
- Additionally, Massarotti's work investigates SIRT2 as a promising therapeutic target, leading to the development of selective inhibitors through novel chemical scaffolds that enhance the understanding of SIRT2's role in various diseases, including cancer and neurological disorders.