Publications by authors named "Alberto Maceda Serrano"
Background An increase in epicardial fat thickness (EFT) has been associated with increased cardiovascular risk and the development of atherosclerosis. Transthoracic echo-cardiography provides a reliable measurement of EFT. We evaluated the relationship of EFT with carotid intima-media thickness (CIMT) and ankle-brachial index (ABI), in patients with metabolic syndrome.
View Article and Find Full Text PDFEpicardial fat thickness, but not intraabdominal fat, correlates with intima-media thickness in patients with metabolic syndrome: Epicardial fat and intima-media thickness.
Obes Res Clin Pract
July 2020
Background: Biopterins have a crucial role in the function of nitric oxide synthase, uncoupling of the enzyme leads to endothelial dysfunction and vascular damage, The aim of this study was to evaluate the relationship between the levels of biopterins with carotid intima-media thickness (CIMT) in hypertensive type-2 diabetic patients.
Methods: We studied 30 hypertensive type-2 diabetic patients and 30 normotensive non-diabetic age-matched subjects, in whom biopterins levels were measured by reverse phase high performance liquid chromatography with fluorescence detection. Additionally, the CIMT of both the common and internal carotid arteries was measured.
Background: Hypoadiponectinemia and hyperresistinemia are associated with cardiovascular disease. The increase in the carotid intima-media thickness (CIMT) assessed by B-mode ultrasound has been directly associated with increased risk of myocardial infarction and stroke.
Objective: To evaluate the correlation between adipokine levels with CIMT in hypertensive type 2 diabetic patients.
Article Synopsis
- - The study focuses on the connection between circulating soluble adhesion molecules and atherosclerosis in hypertensive type-2 diabetic patients, highlighting the significant role of inflammation.
- - Researchers measured levels of three molecules (VCAM-1, ICAM-1, E-selectin) and examined the thickness of carotid arteries to assess atherosclerosis in 30 patients.
- - Results showed a notable correlation between ICAM-1 levels and carotid artery thickness, suggesting ICAM-1 may be a key factor in atherosclerosis among this patient group, while VCAM-1 and E-selectin showed no correlation.
Correlation between the levels of circulating adhesion molecules and atherosclerosis in type-2 diabetic normotensive patients: circulating adhesion molecules and atherosclerosis.
Cell Adh Migr
March 2010
Unlabelled: Endothelial dysfunction is a common feature in type-2 diabetic patients and is associated with inflammation, increased levels of circulating soluble adhesion molecules and atherosclerosis. The aim of this study was to evaluate the relationship between the levels of circulating soluble adhesion molecules and the degree of atherosclerosis in normotensive type-2 diabetic patients.
Results: We found significant correlations between ICAM-1 (r = 0.