Publications by authors named "Alberto Locante"
Article Synopsis
- Kaposi sarcoma (KS) is a type of cancer linked to human gammaherpesvirus 8 (HHV-8) and has four subtypes, with iatrogenic KS being extremely rare and often associated with TNF-α inhibitor therapy.
- A 66-year-old woman with rheumatoid arthritis developed a skin lesion after starting treatment with adalimumab, leading to a biopsy that confirmed a diagnosis of iatrogenic KS.
- Due to the risks associated with TNF-α inhibitors, including higher chances of infections and malignancy, careful monitoring and regular skin evaluations are crucial for patients on these treatments.
Thyroid malignancies are one of the fastest growing cancers in the world, with the majority being papillary thyroid cancer. Follicular variant of papillary thyroid cancer accounts for about 10%-20% of papillary thyroid carcinomas. The usual sites for metastases of these tumours are lungs and bones with renal metastases being extremely rare.
View Article and Find Full Text PDFAnisonucleosis is defined as a morphological manifestation of nuclear injury characterized by variation in the size of the cell nuclei. It has been described in variety of benign conditions and is most pronounced in dysplasia and malignancy. To better understand the pathogenesis of anisonucleosis in liver diseases, this study focused on hepatocyte anisonucleosis in biopsies of liver transplant recipients who developed recurrent chronic hepatitis C virus (HCV) infection.
View Article and Find Full Text PDFThere are very limited data concerning the association of lymphocytic thyroiditis with cardiomyopathy, and there is only one published report of fatal cardiomyopathy associated with autoimmune thyroiditis. An association of Hashimoto encephalopathy (HE) with autoimmune myocarditis has not yet been reported. Here we describe a case of a 31-year-old man with autoimmune thyroiditis complicated by HE, who succumbed to autoimmune myocarditis.
View Article and Find Full Text PDFBackground: Sampling error is a common explanation of noncorrelation in women whose Papanicolaou (Pap) tests show high-grade intraepithelial lesions (HSIL) but whose follow-up cervical biopsies show only cervical intraepithelial neoplasia (CIN) 1, koilocytosis, or reactive/inflammatory changes. The purpose of this study was to demonstrate the validity of sampling error in this setting by determining the proportion of negative colposcopic cervical biopsies in women with HSIL who subsequently undergo cone/loop electrode excision procedure (LEEP) biopsies or repeat cervical biopsies that confirm the diagnosis of high-grade CIN (HGCIN).
Methods: In all, 368 cases of HSIL were retrieved from the computerized database from January 1, 2003 to December 31, 2005.