Publications by authors named "Alberto Lai"
Article Synopsis
- The study examines how variations in KIR genes and their interactions with HLA Class I ligands affect the severity of COVID-19 in 396 Sardinian patients.
- Researchers divided patients into two groups: symptomatic or mildly symptomatic (Group A) and hospitalized patients with severe disease (Group S).
- Findings showed significant genetic differences, with Group S having a higher frequency of the KIR A/A haplotype and less representation of the KIR2DS2/HLA C1 combination, indicating these factors may correlate with more severe disease outcomes.
Aim: SARS-CoV-2 infection is a world-wide public health problem. Several aspects of its pathogenesis and the related clinical consequences still need elucidation. In Italy, Sardinia has had very low numbers of infections.
View Article and Find Full Text PDFBackground: The purpose of this study was to use hypnosis in patients with congenital heart disease undergoing transesophageal echocardiography (TEE).
Methods: From January 2016 to July 2017, 50 adult patients undergoing TEE were randomly assigned to two groups: TEE in hypnosis (n = 23), TEE in sedation (n = 27). Vital parameters (heart rate [HR], blood pressure [BP], oxygen saturation [SO2] before, during and after the procedure) and drug administration were recorded.
Objectives: to explore clinicians vision on hospital discharge records in order to identify useful elements to foster a more accurate compiling.
Design: qualitative research with phenomenological approach.
Setting And Participants: participants were selected through purposive sampling among clinicians of two hospitals located in Sardinia; the sample included 76 people (32 medical directors and 44 doctors in training).
Purpose: Healthcare-associated respiratory tract infections are common and markedly affect the quality of life and mortality, as well as increasing costs for health systems due to prolonged hospitalisation. This study aimed to assess the change in both level and trend of respiratory tract infections after a specific hand hygiene program for intensive care unit (ICU) staff.
Materials And Methods: The infection data collection was carried out from January 2013 to August 2014.
Background: Nursing students can be exposed to patients with hepatitis A virus (HAV) and can represent a vehicle of transmission both for health personnel, patients and relatives.
Objectives: The aim of this study was to assess the risk of HAV infection in nursing students during their internship.
Patients And Methods: A seroprevalence survey on HAV infection was performed on nursing students at the Cagliari university-hospital, together with the assessment of the compliance to preventive measures to decrease the risk of infection during their internship.