Publications by authors named "Alberto J Napoli"
Mol Biochem Parasitol
May 2013
Article Synopsis
- * Aminoacyl-tRNA synthetases, crucial for protein synthesis, are identified as promising drug targets against malaria, with the study focusing on the crystal structures of the Pf-cTrpRS enzyme in different states.
- * The structural analysis reveals significant conformational changes in Pf-cTrpRS when bound to the ligand WAMP, suggesting potential avenues for creating selective inhibitors that could lead to new anti-malaria treatments.
