Optimizing the precision of laser speckle contrast imaging.

Laser speckle contrast imaging (LSCI) is a rapidly developing technology broadly applied for the full-field characterization of tissue perfusion. Over the recent years, significant advancements have been made in interpreting LSCI measurements and improving the technique's accuracy. On the other hand, the method's precision has yet to be studied in detail, despite being as important as accuracy for many biomedical applications.

Lossless temporal contrast analysis of laser speckle images from periodic signals.

Laser speckle contrast imaging is a technique that provides valuable physiological information about vascular topology and blood flow dynamics. When using contrast analysis, it is possible to obtain detailed spatial information at the cost of sacrificing temporal resolution and vice versa. Such a trade-off becomes problematic when assessing blood dynamics in narrow vessels.