[Factors linked to rapid progression to AIDS in Cuban subjects].

Introduction: in the last few years, the number of HIV Cuban patients expressing rapid clinical and immunologic deterioration has increased.

Objective: to find out the possible factors associated to rapid progression to AIDS.

Methods: a case-control study was carried out with the objective of determining possible factors associated with rapid progression to AIDS.

Achieving sustainability of community-based dengue control in Santiago de Cuba.

Achieving sustainability is one of the major current challenges in disease control programmes. In 2001-2002, a community-based dengue control intervention was developed in three health zones of Santiago de Cuba. New structures (heterogeneous community working groups and provincial/municipal coordination groups inserted in the vertical programme) were formed and constituted a key element to achieve social mobilization.

[Community participation in Dengue prevention: an approach from the perspective of different social actors].

Objective: To explore the perceptions about community participation in dengue fever control during formative research for a community project.

Material And Methods: This study was conducted in three health areas of the Santiago de Cuba municipality during the year 2000. Qualitative and quantitative techniques were used to explore the opinions of health professionals, community leaders and a random sample of 200 people living in the community.

[Reactogenecity and immunogenecity of Cuban trivalent inactivated vaccine against human leptospirosis in different vaccination schedules].

A controlled, randomized assay was performed to evaluate the reactogenecity and immunogenecity of Cuban trivalent vaccine against human leptospirosis (vax-SPIRAL) in healthy volunteers, using different vaccination schemes. A Russian-made vaccine was used as control. Adverse effects were local symptoms and signs (pain, rush, local infiltration, itching, necrosis and abscess) and general symptoms and signs(fever, low-grade fever, headache, lipotimia, nausea, vomiting, rash and general malaise).

Naturally acquired immunity to Haemophilus influenzae type B in healthy Cuban children.

We have evaluated the prevalence of antibody to immunogenicity of Haemophilus influenzae type b (Hib) in a group of 4 to 5 years old healthy children, who were too old to be included in the first vaccinated cohort when Hib vaccination begun in Cuba in 1999. Serum capsular polysaccharide specific IgG antibody concentrations were measured in 974 healthy children, between February and May 2002. The prevalence of Hib nasopharyngeal carriage was also estimated.