In Vitro Evaluation of Rosemary Essential Oil: GC-MS Profiling, Antibacterial Synergy, and Biofilm Inhibition.

Antimicrobial resistance (AMR) has become precarious, warranting investments in antimicrobial discovery. To investigate the antibacterial activity of rosemary essential oil (REO), alone and in combination with selected conventional antibiotics. REO was subjected to antimicrobial susceptibility testing (including minimum bactericidal concentration (MBC) and minimum inhibitory concentration (MIC) determination) and investigation of anti-pre-biofilm and antibiofilm activities.

Multidrug-Resistant Bacteria in Aquaculture Systems in Accra, Ghana.

Background: Antibiotic resistance (ABR) poses a critical global health challenge, necessitating its surveillance across both human and animal health sectors. This study evaluated ABR in bacteria harboured in reared inland fishes sold in Accra and the pond water from which they originated.

Method: The study was cross-sectional, involving fishes and water sampled from 80 ponds.

In Vitro effects of petroleum ether, dichloromethane, methanolic and aqueous leaf extracts of Eucalyptus grandis on selected multidrug-resistant bacteria.

Background: The emergence and spread of antimicrobial resistance is of grave concern, requiring the search for newer and more effective antimicrobials to combat infections caused by resistant microbes. This study assessed the antimicrobial effects of Eucalyptus grandis crude extracts against selected multidrug resistant bacteria.

Methodology: Four different crude leaf extracts of E.

Occurrence, ecological risk assessment and source apportionment of pharmaceuticals, steroid hormones and xenoestrogens in the Ghanaian aquatic environments.

Elevated levels of pharmaceuticals, steroid hormones and xenoestrogens (PSHXEs) in the aquatic environment pose a serious threat to the ecological balance. The endocrine disrupting PSHXEs in aquatic systems are linked to several adverse effects like reproductive health impairment, feminization, high mortality rate, decreased biodiversity etc. This study, therefore, sought to investigate the occurrence and the ecological risks posed by some selected PSHXEs and also conduct source apportionment of the PSHXEs in the Ghanaian aquatic environments.

Nasopharyngeal Carriage and Antimicrobial Resistance among Adults with Sickle Cell Disease at the Korle Bu Teaching Hospital in Accra, Ghana.

Background: Sickle cell disease (SCD) patients are an important risk group for () carriage and infections. Little is, however, known about the nasopharyngeal carriage epidemiology of the pathogen in this vulnerable population.

Aim: The aim of this study was to evaluate and methicillin-resistant (MRSA) nasopharyngeal carriage prevalence, carriage determinants, and antimicrobial resistance among SCD adults in Ghana.