Request Dispatching Over Distributed SDN Control Plane: A Multiagent Approach.

Software-defined networking (SDN) allows flexible and centralized control in cloud data centers. An elastic set of distributed SDN controllers is often required to provide sufficient yet cost-effective processing capacity. However, this introduces a new challenge: Request Dispatching among the controllers by SDN switches.

On enabling collaborative non-intrusive load monitoring for sustainable smart cities.

Improving energy efficiency is a crucial aspect of building a sustainable smart city and, more broadly, relevant for improving environmental, economic, and social well-being. Non-intrusive load monitoring (NILM) is a computing technique that estimates energy consumption in real-time and helps raise energy awareness among users to facilitate energy management. Most NILM solutions are still a single machine approach and do not fit well in smart cities.

Fine-Grained Lesion Classification Framework for Early Auxiliary Diagnosis.

The deep neural networks are envisaged for the early disease diagnosis from medical images. However, in the early stage of the disease, the medical images of patients and healthy people have only subtle visual differences. Distinguishing the medical images for early diagnosis belongs to the Fine-Grained Visual Classification (FGVC) task.

Efficient and Effective One-Step Multiview Clustering.

Multiview clustering algorithms have attracted intensive attention and achieved superior performance in various fields recently. Despite the great success of multiview clustering methods in realistic applications, we observe that most of them are difficult to apply to large-scale datasets due to their cubic complexity. Moreover, they usually use a two-stage scheme to obtain the discrete clustering labels, which inevitably causes a suboptimal solution.

Region-Aware Hierarchical Latent Feature Representation Learning-Guided Clustering for Hyperspectral Band Selection.

Hyperspectral band selection aims to identify an optimal subset of bands for hyperspectral images (HSIs). For most existing clustering-based band selection methods, they directly stretch each band into a single feature vector and employ the pixelwise features to address band redundancy. In this way, they do not take full consideration of the spatial information and deal with the importance of different regions in HSIs, which leads to a nonoptimal selection.

Prediction of Sepsis in COVID-19 Using Laboratory Indicators.

Background: The outbreak of coronavirus disease 2019 (COVID-19) has become a global public health concern. Many inpatients with COVID-19 have shown clinical symptoms related to sepsis, which will aggravate the deterioration of patients' condition. We aim to diagnose Viral Sepsis Caused by SARS-CoV-2 by analyzing laboratory test data of patients with COVID-19 and establish an early predictive model for sepsis risk among patients with COVID-19.

DeFusionNET: Defocus Blur Detection via Recurrently Fusing and Refining Discriminative Multi-Scale Deep Features.

Albeit great success has been achieved in image defocus blur detection, there are still several unsolved challenges, e.g., interference of background clutter, scale sensitivity and missing boundary details of blur regions.

Temporal Convolutional Networks for the Advance Prediction of ENSO.

El Niño-Southern Oscillation (ENSO), which is one of the main drivers of Earth's inter-annual climate variability, often causes a wide range of climate anomalies, and the advance prediction of ENSO is always an important and challenging scientific issue. Since a unified and complete ENSO theory has yet to be established, people often use related indicators, such as the Niño 3.4 index and southern oscillation index (SOI), to predict the development trends of ENSO through appropriate numerical simulation models.

Fingerprint Identification With Shallow Multifeature View Classifier.

This article presents an efficient fingerprint identification system that implements an initial classification for search-space reduction followed by minutiae neighbor-based feature encoding and matching. The current state-of-the-art fingerprint classification methods use a deep convolutional neural network (DCNN) to assign confidence for the classification prediction, and based on this prediction, the input fingerprint is matched with only the subset of the database that belongs to the predicted class. It can be observed for the DCNNs that as the architectures deepen, the farthest layers of the network learn more abstract information from the input images that result in higher prediction accuracies.

Reduction of Artefacts in JPEG-XR Compressed Images.

The JPEG-XR encoding process utilizes two types of transform operations: Photo Overlap Transform (POT) and Photo Core Transform (PCT). Using the Device Porting Kit (DPK) provided by Microsoft, we performed encoding and decoding processes on JPEG XR images. It was discovered that when the quantization parameter is >1-lossy compression conditions, the resulting image displays chequerboard block artefacts, border artefacts and corner artefacts.

AdaSampling for Positive-Unlabeled and Label Noise Learning With Bioinformatics Applications.

Class labels are required for supervised learning but may be corrupted or missing in various applications. In binary classification, for example, when only a subset of positive instances is labeled whereas the remaining are unlabeled, positive-unlabeled (PU) learning is required to model from both positive and unlabeled data. Similarly, when class labels are corrupted by mislabeled instances, methods are needed for learning in the presence of class label noise (LN).

RadixHap: a radix tree-based heuristic for solving the single individual haplotyping problem.

Single nucleotide polymorphism studies have recently received significant amount of attention from researchers in many life science disciplines. Previous researches indicated that a series of SNPs from the same chromosome, called haplotype, contains more information than individual SNPs. Hence, discovering ways to reconstruct reliable Single Individual Haplotypes becomes one of the core issues in the whole-genome research nowadays.

Sample Subset Optimization Techniques for Imbalanced and Ensemble Learning Problems in Bioinformatics Applications.

Data sampling is a widely used technique in a broad range of machine learning problems. Traditional sampling approaches generally rely on random resampling from a given dataset. However, these approaches do not take into consideration additional information, such as sample quality and usefulness.

Using genetic algorithm in reconstructing single individual haplotype with minimum error correction.

Discovering ways to reconstruct reliable Single Individual Haplotypes (SIHs) becomes one of the core issues in the whole-genome research nowadays as previous research showed that haplotypes contain more information than individual Singular Nucleotide Polymorphisms (SNPs). Although with advances in high-throughput sequencing technologies obtaining sequence information is becoming easier in today's laboratories, obtained sequences from current technologies always contain inevitable sequence errors and missing information. The SIH reconstruction problem can be formulated as bi-partitioning the input SNP fragment matrix into paternal and maternal sections to achieve minimum error correction (MEC) time; the problem that is proved to be NP-hard.

Coherent information structure in complex computation.

We have recently presented a framework for the information dynamics of distributed computation that locally identifies the component operations of information storage, transfer, and modification. We have observed that while these component operations exist to some extent in all types of computation, complex computation is distinguished in having coherent structure in its local information dynamics profiles. In this article, we conjecture that coherent information structure is a defining feature of complex computation, particularly in biological systems or artificially evolved computation that solves human-understandable tasks.

Hierarchical kernel mixture models for the prediction of AIDS disease progression using HIV structural gp120 profiles.

Changes to the glycosylation profile on HIV gp120 can influence viral pathogenesis and alter AIDS disease progression. The characterization of glycosylation differences at the sequence level is inadequate as the placement of carbohydrates is structurally complex. However, no structural framework is available to date for the study of HIV disease progression.

A genetic ensemble approach for gene-gene interaction identification.

Background: It has now become clear that gene-gene interactions and gene-environment interactions are ubiquitous and fundamental mechanisms for the development of complex diseases. Though a considerable effort has been put into developing statistical models and algorithmic strategies for identifying such interactions, the accurate identification of those genetic interactions has been proven to be very challenging.

Methods: In this paper, we propose a new approach for identifying such gene-gene and gene-environment interactions underlying complex diseases.

Information modification and particle collisions in distributed computation.

Distributed computation can be described in terms of the fundamental operations of information storage, transfer, and modification. To describe the dynamics of information in computation, we need to quantify these operations on a local scale in space and time. In this paper we extend previous work regarding the local quantification of information storage and transfer, to explore how information modification can be quantified at each spatiotemporal point in a system.

A novel integrative phylogenetic analysis system.

Existing phylogenetic methods cannot realistically model the evolutionary process. It has become a serious issue for real-life applications which demand accurate phylogenetic results. It is desirable to have an integrative approach which can effectively incorporate multi-disciplinary analyses and synthesise results from various sources.

A multi-filter enhanced genetic ensemble system for gene selection and sample classification of microarray data.

Background: Feature selection techniques are critical to the analysis of high dimensional datasets. This is especially true in gene selection from microarray data which are commonly with extremely high feature-to-sample ratio. In addition to the essential objectives such as to reduce data noise, to reduce data redundancy, to improve sample classification accuracy, and to improve model generalization property, feature selection also helps biologists to focus on the selected genes to further validate their biological hypotheses.

RBT-L: a location based approach for solving the Multiple Sequence Alignment problem.

This paper presents a novel approach to solve the Multiple Sequence Alignment (MSA) problem. The Rubber Band Technique: Location Base (RBT-L) introduced in this paper, is inspired by the elastic behaviour of a Rubber Band (RB) on a plate with poles. RBT-L is an iterative optimisation algorithm designed and implemented to find the optimal alignment for a set of input protein sequences.

A particle swarm based hybrid system for imbalanced medical data sampling.

Background: Medical and biological data are commonly with small sample size, missing values, and most importantly, imbalanced class distribution. In this study we propose a particle swarm based hybrid system for remedying the class imbalance problem in medical and biological data mining. This hybrid system combines the particle swarm optimization (PSO) algorithm with multiple classifiers and evaluation metrics for evaluation fusion.

A modular kernel approach for integrative analysis of protein domain boundaries.

Background: In this paper, we introduce a novel inter-range interaction integrated approach for protein domain boundary prediction. It involves (1) the design of modular kernel algorithm, which is able to effectively exploit the information of non-local interactions in amino acids, and (2) the development of a novel profile that can provide suitable information to the algorithm. One of the key features of this profiling technique is the use of multiple structural alignments of remote homologues to create an extended sequence profile and combines the structural information with suitable chemical information that plays an important role in protein stability.

RBT-GA: a novel metaheuristic for solving the Multiple Sequence Alignment problem.

Background: Multiple Sequence Alignment (MSA) has always been an active area of research in Bioinformatics. MSA is mainly focused on discovering biologically meaningful relationships among different sequences or proteins in order to investigate the underlying main characteristics/functions. This information is also used to generate phylogenetic trees.

Analysis of protein phosphorylation site predictors with an independent dataset.

Protein phosphorylation plays a fundamental role in most of the cellular regulatory pathways. Experimental detection of protein phosphorylation sites is labour intensive and often limited by the availability and optimisation of enzymatic reactions. The in silico prediction of phosphorylation sites using protein's primary sequences may provide guidelines for further experimental consideration and interpretation of phosphoproteomic data.