Asthma in the elderly: the effect of choline supplementation.

Background: Asthma in the elderly is poorly understood as very few studies have included these patients. DNA methylation can affect the expression of asthma susceptibility genes. Methyl groups can be produced through a choline dependent pathway.

Asthma in the elderly: a study of the role of vitamin D.

Background: Asthma in the elderly is poorly understood and vitamin D deficiency and insufficiency are very common in older individuals. We studied the role of vitamin D in elderly asthmatics.

Methods: Asthmatics subjects, age 65 and older, were followed every 4 weeks for 12 weeks in the late fall and winter.

The effect of multiple allergen immunotherapy on exhaled nitric oxide in adults with allergic rhinitis.

Background: There is a lack of objective measures of the clinical efficacy of allergen immunotherapy which relies on patients' perception about the effect of this treatment. We studied whether the fraction of exhaled nitric oxide is affected by multiple allergen immunotherapy in polysensitized adult subjects with allergic rhinitis. We also looked for associations between exhaled nitric oxide and subjects' demographics, symptom scores, and pulmonary function tests.

Asthma in the elderly: the role of exhaled nitric oxide measurements.

Asthma in the elderly is poorly understood because only a small minority of asthma studies have investigated this patients group. Fractional exhaled nitric oxide (FENO) has been extensively studied in children and adults with asthma, but little is known about FENO in elderly asthmatics. We studied the role of serial measurements of FENO in elderly subjects with asthma.