Publications by authors named "Albert Perlas"

Neurobrucellosis in cetaceans, caused by , is a relevant cause of death in striped dolphins () from the Mediterranean Sea. Serological tests are not used as a routinary technique for the diagnosis of this infection. We briefly describe the pathological findings of nine free-ranging stranded cetaceans diagnosed with disease or infection in our veterinary necropsy service from 2012 to 2022.

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High pathogenicity avian influenza viruses (HPAIVs) have caused major epizootics in recent years, with devastating consequences for poultry and wildlife worldwide. Domestic and wild ducks can be highly susceptible to HPAIVs, and infection leads to efficient viral replication and massive shedding (i.e.

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While the air microbiome and its diversity are essential for human health and ecosystem resilience, comprehensive air microbial diversity monitoring has remained rare, so that little is known about the air microbiome's composition, distribution, or functionality. Here we show that nanopore sequencing-based metagenomics can robustly assess the air microbiome in combination with active air sampling through liquid impingement and tailored computational analysis. We provide fast and portable laboratory and computational approaches for air microbiome profiling, which we leverage to robustly assess the taxonomic composition of the core air microbiome of a controlled greenhouse environment and of a natural outdoor environment.

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Article Synopsis
  • Real-time genomics using nanopore sequencing can quickly predict antibiotic resistance in clinical settings, which is crucial for timely treatment.
  • Despite some accuracy concerns compared to traditional methods, this approach can accurately identify low-abundance resistance factors often missed by conventional diagnostics.
  • The study highlights that real-time genomic analysis can greatly enhance clinical decision-making by revealing hidden resistance profiles, ultimately improving patient outcomes.
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Immature feathers are known replication sites for high pathogenicity avian influenza viruses (HPAIVs) in poultry. However, it is unclear whether feathers play an active role in viral transmission. This study aims to investigate the contribution of the feather epithelium to the dissemination of clade 2.

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Article Synopsis
  • The ongoing environmental degradation is challenging our understanding of the interconnectedness of human and environmental health, a concept known as One Health.
  • Real-time genomic analyses, particularly nanopore sequencing, can enhance our ability to assess ecosystem health by providing quick and detailed insights into various environmental and health-related issues.
  • The implementation of these genomic technologies raises important considerations regarding equitable access, as well as practical, legal, and ethical challenges that must be addressed.
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Avian influenza viruses (AIVs) can affect wildlife, poultry, and humans, so a One Health perspective is needed to optimize mitigation strategies. Migratory waterfowl globally spread AIVs over long distances. Therefore, the study of AIV persistence in waterfowl staging and breeding areas is key to understanding their transmission dynamics and optimizing management strategies.

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Highly pathogenic avian influenza viruses (HPAIVs) cause severe systemic disease and high mortality rates in chickens, leading to a huge economic impact in the poultry sector. However, some chickens are resistant to the disease. This study aimed at evaluating the mechanisms behind HPAIV disease resistance.

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Chickens are highly susceptible to highly pathogenic avian influenza viruses (HPAIVs). However, the severity of infection varies depending of the viral strain and the genetic background of the host. In this study, we evaluated the pathogenesis of two HPAIVs (H7N1 and H5N8) and assessed the susceptibility to the infection of local and commercial chicken breeds from Spain.

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