Publications by authors named "Albert K Neto"
Article Synopsis
- Novel benzophenone-thiazole hybrids were created and tested for their ability to reduce inflammation in a lab setting using human blood.
- The hybrids displayed impressive inhibition of prostaglandin E2 (PGE2) release, with some showing effectiveness comparable to existing reference drugs.
- Molecular docking studies suggest these hybrids can bind effectively to key enzymes involved in inflammation, indicating their potential as new anti-inflammatory drug candidates and emphasizing the importance of choosing the right chemical substituents.
The Lauraceae is a botanical family known for its anti-inflammatory potential. However, several species have not yet been studied. Thus, this work aimed to screen the anti-inflammatory activity of this plant family and to build statistical prediction models.
View Article and Find Full Text PDFOwing to the potentially harmful adverse effects of current anti-inflammatory drugs, there is a need to identify new alternative substances. Thus, this study aimed to perform a phytochemical analysis of to identify compounds responsible for its anti-inflammatory activity. Several fractions of the extract were obtained and evaluated in an anti-inflammatory assay using fresh human blood.
View Article and Find Full Text PDFbicyclic [3.2.1] octane neolignans have garnered increasing interest, because of their unique structural features and biological activities.
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