Publications by authors named "Albert Gyllencreutz Castellheim"
Background: Chemical, biological and nerve gas events have a significant impact on public health, necessitating proper education and training. This study investigated the educational needs as perceived by two groups, frontline healthcare workers and medical students, in relation to chemical, biological, and nerve gas events.
Methods: Three distinct web-based cross-sectional surveys were conducted, one each for chemical, biological, and nerve gas events, with each survey following the same structural format including sections on (a) theoretical knowledge assessment, using multiple-choice questions regarding identification, protection, and treatment, (b) perception of threat, using questions based on a 5-point Likert scale to gauge views on threat/preparedness and (c) perception of existing competency, with questions regarding prior education and the need for additional education and training.
Objectives: Considering that the remission rate for major depressive disorder (MDD) in elderly patients is below 50%, there is a compelling requirement for an enhanced comprehension of the underlying mechanisms. Chronic low-grade inflammation has been posited as one potential contributor to treatment-resistant MDD in the elderly. Accordingly, the objective of our study was to explore the longitudinal trends of systemic immune markers in elderly inpatients referred to electroconvulsive therapy due to an episode of treatment resistant unipolar MDD.
View Article and Find Full Text PDFUnraveling the inflammatory narrative: A rejoinder to a curious tale.
Acta Anaesthesiol Scand
August 2024
Background: This study focuses on biomarkers in infants after open heart surgery, and examines the association of high-sensitive troponin T (hs-cTnT), interleukin-6 (IL-6), and interleukin-8 (IL-8) with postoperative acute kidney injury (AKI), ventilatory support time and need of vasoactive drugs.
Methods: Secondary exploratory study from a double-blinded clinical randomized trial (Mile-1) on 70 infants undergoing open heart surgery with cardiopulmonary bypass (CPB). In this sub-study, the entire study population was examined without considering the study drugs.
Article Synopsis
- A study analyzed 30-day and 10-year survival rates in children and young adults after out-of-hospital cardiac arrest (OHCA) in Sweden over the past 30 years.
- The research showed a significant increase in 30-day survival rates, rising from 7% to 20%, with a notable decrease in time to CPR from 14 to 2 minutes.
- Although survival rates improved, particularly among those who survived the first 30 days, overall mortality remains high, highlighting the need for ongoing efforts to address risk factors and improve outcomes.
Article Synopsis
- Mortality rates for pediatric patients with tetralogy of Fallot (TOF) have significantly decreased since surgical interventions began in the 1950s, yet comprehensive survival data in Sweden remains limited.
- This study aimed to analyze survival trends of children with TOF and compare them to similarly matched controls using a nationwide dataset from Sweden spanning nearly five decades.
- The results indicated that of 1,848 patients with TOF, 15.5% died during follow-up, with a notable 10.1% mortality rate in those who underwent surgery, highlighting improved survival rates over different birth periods.
Introduction: The neonate and children audit of anaesthesia practice in Europe (NECTARINE) prospective observational study reported an incidence of 35.2% of critical events requiring intervention during 6542 anaesthetics in 5609 infants up to 60 weeks postmenstrual age (PMA) from 165 centres in 31 European countries.
Methods: Sub-analysis of the cohort from the Nordic countries (8% of the entire cohort) was conducted.