Publications by authors named "Albert Gordon Smith"

Diabetic peripheral neuropathy and metabolic syndrome (MetS) are both global health challenges with well-established diagnostic criteria and significant impacts on quality of life. Clinical observations, epidemiologic evidence, and animal models of disease have strongly suggested MetS is associated with an elevated risk for cryptogenic sensory peripheral neuropathy (CSPN). MetS neuropathy preferentially affects small unmyelinated axons early in its course, and it may also affect autonomic and large fibers.

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Article Synopsis
  • The study aimed to evaluate a new care model, SymptomCare@Home (SCH), to reduce neuropathic symptoms caused by chemotherapy.
  • Participants were randomized into usual care or SCH, where SCH included daily automated symptom reporting and nurse practitioner follow-up for moderate to severe symptoms.
  • Results showed that SCH significantly reduced the days with moderate and severe neuropathic symptoms and related distress compared to usual care.
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In order to develop an efficient, reproducible, and well-tolerated protocol for assessing corneal innervation, 11 normal subjects underwent corneal confocal microscopy (CCM) using a Heidelberg Retinal Tomography III microscope. Five standardized locations were sampled in the left eye and one centrally in the right. The protocol was repeated 1-4 weeks later.

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