Publications by authors named "Albert Cheung"
Purpose: This study sought to determine the effect of donor preservation time and other donor tissue factors on the clinical outcomes of keratolimbal allograft (KLAL) transplantation.
Methods: In this retrospective chart review of patients who underwent KLAL transplantation, electronic health records were reviewed for relevant patient ocular and surgical history. Donor tissue factors were collected from donor reports.
Evaluation of the Efficacy of a Novel Dermatotomy Device for Central Venous Cannulation.
J Cardiothorac Vasc Anesth
September 2024
Objective: To test the effectiveness of a novel wire-guided scalpel (Guideblade) to create a precise dermatotomy incision for central venous catheter (CVC) insertion.
Design: Prospective, nonrandomized interventional study.
Setting: Stanford University, single-center teaching hospital.
Purpose: The purposes of this study were to bring awareness to the surgical waste generated from corneal and conjunctival surgeries and to compare those findings with the waste generated from cataract surgeries.
Methods: This was an observational prospective pilot cohort study at a tertiary corneal/anterior segment private practice. All waste related to cataract, cornea, and conjunctival surgical procedures (including anesthesia waste and corneal tissue storage) was weighed.
Purpose: The purpose of this study was to describe the use of Descemet membrane anterior keratoplasty (DMAK) with modified allogeneic simple limbal epithelial transplantation to treat a case of partial limbal stem cell deficiency (LSCD) following keratolimbal allograft failure.
Methods: Case report.
Results: A 21-year-old woman with autoimmune polyglandular syndrome-related LSCD presented with pain and decreased vision.
Purpose: To highlight the paucity of surgeons performing ocular surface stem cell transplantation with systemic immunosuppression (OSSTx with SI) for limbal stem cell deficiency (LSCD) patients, suboptimal treatments for LSCD, and obstacles to adoption.
Methods: A review of the Eye Bank Association of America annual reports and the authors' case volume for OSSTx with SI was performed. Examination of the published literature on corneal surgeries, especially for LSCD, was completed.
Even though the central role of mechanics in the cardiovascular system is widely recognized, estimating mechanical deformation and strains in-vivo remains an ongoing practical challenge. Herein, we present a semi-automated framework to estimate strains from four-dimensional (4D) echocardiographic images and apply it to the aortic roots of patients with normal trileaflet aortic valves (TAV) and congenital bicuspid aortic valves (BAV). The method is based on fully nonlinear shell-based kinematics, which divides the strains into in-plane (shear and dilatational) and out-of-plane components.
View Article and Find Full Text PDFPurpose: The aim of this study was to describe the use of intravenous immunoglobulin (IVIG) in the management of a 20-year-old woman with autoimmune polyglandular syndrome-associated keratopathy who developed acute transplant rejection after keratolimbal allograft (KLAL) surgery.
Case: Nine weeks after KLAL surgery, a 20-year-old woman with autoimmune polyglandular syndrome-related limbal stem cell deficiency presented with graft injection, hemorrhage, and an epithelial rejection line. This was concerning for acute rejection in the setting of triple-agent systemic immunosuppression (albeit nonadherence at times).
Purpose: The aim of this study was to report outcomes after allogeneic ocular surface stem cell transplantation (OSST) for limbal stem cell deficiency in the setting of decreased or no systemic immunosuppression (SI) in the elderly.
Methods: A retrospective chart review was performed of all eyes that underwent OSST for limbal stem cell deficiency between 2005 and 2020 at CVP Physicians. Inclusion criteria included patients who were (1) at least 70 years at the time of (2) allogeneic OSST.
fungal keratitis: An initial case report and species identification.
Am J Ophthalmol Case Rep
March 2023
Article Synopsis
- A 66-year-old man with a complicated eye history developed a rare case of fungal keratitis caused by a specific filamentous fungus, despite having no prior eye trauma.
- His treatment involved multiple interventions, including antifungal medications, corneal surgeries, and even hospitalizations for complications, but the infections recurred and led to severe complications, including corneal perforation.
- The case highlights the challenges and potential for recurrence in treating this type of fungal keratitis, ultimately leading to the patient's decline in health due to other underlying issues.
Purpose: This report describes a case and management of a 69-year-old female with infectious scleritis found to be caused by species.
Observations: Our patient presented with severe constant pain in the left eye (OS) following cataract surgery. She had a pertinent past medical history significant for renal transplantation (on oral tacrolimus, mycophenolate, and prednisone).
Purpose: To compare cryopreserved sutureless amniotic membrane (C-SAM) and dehydrated SAM (D-SAM) outpatient treatment outcomes for persistent epithelial defects (PEDs), analyze risk factors for treatment failure, and identify adverse events.
Design: Retrospective, interventional comparative clinical study.
Methods: This study was a multicenter retrospective interventional cohort from 2 tertiary corneal referral practices from 2016 to 2020.
Article Synopsis
- The study aimed to analyze experiences with Descemet membrane (DM) ruptures during deep anterior lamellar keratoplasty (DALK) procedures over a 15-year period.
- Out of 1,443 eyes evaluated, DM ruptures were found in 119 (8.25%), mostly as microruptures occurring in manual DALK, with most cases resolving quickly post-surgery.
- The average endothelial cell loss was 19% after one year, and the majority of grafts remained clear, highlighting that while DM ruptures can complicate surgery, they generally resolve effectively.
Article Synopsis
- The study aimed to examine how the number of penetrating keratoplasty (PK) procedures affects postoperative panel reactive antibody (PRA) levels and the number of unacceptable antigens in patients.
- A cross-sectional study was conducted, excluding patients with solid organ transplants, pregnancy, or blood transfusions, and focused on comparing patients with single vs. multiple PKs.
- Results showed that those with multiple PKs had higher PRA levels and a greater number of unacceptable antigens, indicating a correlation between the number of PKs and PRA levels that warrants further investigation.