Haemophilic arthropathy: long-term outcomes in 107 primary total knee arthroplasties.

Background: Arthropathy of the knee is a frequent complication in patients with severe bleeding disorders leading to considerable pain and disability. Total knee arthroplasty (TKA) provides marked pain relief. However, a modest functional outcome and a high number of complications due to prosthetic infection and loosening are reported.

High mortality rate in rheumatoid arthritis with subluxation of the cervical spine: a cohort study of operated and nonoperated patients.

Study Design: In a prospective cohort study 532 patients with rheumatoid arthritis (RA) and subluxations of the cervical spine were consecutively collected during 1974-1999.

Objective: The aims of the study were to assess important factors affecting the mortality rate and the timing of surgical intervention.

Summary Of Background Data: The average follow-up time from the first visit to death or to the end of the study was 8.

[Surgery in patients with bleeding disorders--expensive treatment for a small group of patients].

Background: During surgical procedures, patients with bleeding disorders have a major risk of bleeding complications. To reduce the risk of bleeding it is necessary to provide pre-, peri- and postoperative antihaemorrhagic therapy. In less severe bleeding disorders, pharmacologic treatment may be sufficient, but in patients with severe bleeding disorders there is always a need for clotting factor concentrates.