Publications by authors named "Albert Albesa-Gonzalez"
Article Synopsis
- Theta-band oscillations (3-8 Hz) in the hippocampus help organize input from the cortex, which is crucial for forming episodic memories and navigating spaces.
- The study introduces a theoretical framework that balances the speed of information sampling and accuracy, revealing that while higher frequencies might seem better, theta oscillations provide an optimal information rate (1-2 bits/s).
- This framework explains key features of the hippocampus, like the consistent presence of theta waves and their modulation by factors like running speed, and suggests that these oscillations may also benefit other brain regions, paving the way for further research on optimal brain functioning.
Filopodia are thin synaptic protrusions that have been long known to play an important role in early development. Recently, they have been found to be more abundant in the adult cortex than previously thought, and more plastic than spines (button-shaped mature synapses). Inspired by these findings, we introduce a new model of synaptic plasticity that jointly describes learning of filopodia and spines.
View Article and Find Full Text PDFModels of synaptic plasticity have been used to better understand neural development as well as learning and memory. One prominent classic model is the Bienenstock-Cooper-Munro (BCM) model that has been particularly successful in explaining plasticity of the visual cortex. Here, in an effort to include more biophysical detail in the BCM model, we incorporate 1) feedforward inhibition, and 2) the experimental observation that large synapses are relatively harder to potentiate than weak ones, while synaptic depression is proportional to the synaptic strength.
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