Publications by authors named "Albayrak Ayse"

Background: This study aimed to identify factors that influence the mortality rate of patients with coronavirus disease (COVID-19)-associated pulmonary aspergillosis (CAPA).

Methods: In this cross-sectional study, data from 23 centers across 15 countries, spanning the period of March 2020 to December 2021, were retrospectively collected. The study population comprised patients who developed invasive pulmonary aspergillosis while being treated for COVID-19 in the intensive care unit.

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Article Synopsis
  • - The COVID-19 pandemic led to a rise in cases of mucormycosis, particularly in India, prompting a study to analyze factors affecting mortality in COVID-19-associated mucormycosis (CAM) among patients in mainly Asian and some African countries.
  • - The study included 162 CAM patients, primarily older males, with a high prevalence of diabetes and rhino-orbital-cerebral mucormycosis; results indicated a 39% mortality rate influenced by advanced age, use of rituximab, and diabetic ketoacidosis as significant risk factors.
  • - Findings suggest that surgical debridement improves survival rates, and combining antifungal treatments with surgery significantly enhances outcomes for CAM patients.
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Background: During the COVID pandemic, research has shown an increase in candidemia cases following severe COVID infection and the identification of risk factors associated with candidemia. However, there is a lack of studies that specifically explore clinical outcomes and mortality rates related to candidemia after COVID infection.

Objectives: The aim of this international study was to evaluate the clinical outcomes and identify factors influencing mortality in patients who developed candidemia during their COVID infection.

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  • The study investigates the clinicopathological characteristics and mortality predictors in patients with peritoneal tuberculosis (TBP) using data from 38 medical centers across 13 countries.
  • A total of 208 TBP patients were analyzed, with common comorbid conditions including HIV, diabetes, and chronic renal failure; 34 (16.3%) of these patients died from TBP.
  • Key mortality risk factors identified include HIV positivity, cirrhosis, advanced age, and specific symptoms, leading to the development of a pioneering mortality predicting model to identify high-risk patients.
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  • The study aimed to analyze laboratory differences among 443 COVID-19 patients at Atatürk University, to improve understanding of disease severity and treatment strategies.
  • Patients were categorized into four clinical groups: asymptomatic, uncomplicated, mild/moderate, and severe, with a breakdown of symptoms and comorbidities noted, revealing hypertension as the most common condition.
  • Key laboratory markers showed significant variance, with severe cases exhibiting higher levels of inflammation and markers like procalcitonin and D-dimer, indicating a potential for worse outcomes, including a 4.7% mortality rate.
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Background: Brucellosis is a worldwide zoonotic disease that causes serious public health problems. This study aimed to identify Brucella strains isolated from various clinical samples by conventional and molecular methods and to determine antimicrobial susceptibilities against doxycycline (DOX), streptomycin (STR), ciprofloxacin (CIP) and rifampicin (RIF) by the gradient strip (E test) test method.

Methods: A total of 87 Brucella strains isolated from various clinical specimens between 2004 and 2018 were included in this study.

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Background: Burns are a primary cause of mortality along with the severe physical and psychological morbidities in patients and their families. Such kinds of injuries bring about considerable financial burdens due to the treatment processes and sequels. The present study aims to investigate the factors that affect the mortality of burns.

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Background/aims: The present study aimed to determine the changes in the epidemiology of hepatitis in recent years in an adult Turkish population.

Materials And Methods: Overall, 852 patients with acute viral hepatitis from 17 centers were included in this study. Their sociodemographic characteristics, clinical courses, treatments, and laboratory findings were retrospectively analyzed.

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Tularemia is a zoonotic infectious disease caused by Francisella tularensis. Tularemia is endemic in the northern hemisphere and is usually seen in North America, Europe and Asia. Although the ulceroglandular tularemia is the most common form in these regions, the oropharyngeal form is more prevalent in Eastern Europe, including Turkey.

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Background: Burn trauma is a significant health problem that has physical, psychological, and economic repercussions on affected patients. The aim of this study was to present epidemiological and demographic characteristics of patients treated over an 8-year period at a reference burn treatment center located in the northeast of Turkey and serving a population of approximately four million people.

Methods: Each patient's medical record was reviewed, and demographic features, source of burns, place of residence, total body surface area (TBSA), surgical treatment, duration of hospital stay, and mortality rates were analyzed.

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Unlabelled: Hydatid cyst is a zoonotic disease seen in endemic areas. It is an important health problem in our country and especially in our Eastern and South-eastern Anatolia Region. Involvement of isolated breast tissue is very rare in hydatid cystdisease.

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Aim: The purpose of this study was to investigate the relationship between the findings from liver biopsy and the serum angiotensin-converting enzyme (ACE) level to determine whether ACE might serve as a potential noninvasive sign of necroinflammatory activity in patients with Chronic Hepatitis B (CHB) infection.

Methods: A total of 54 CHB patients referred for liver biopsy were enrolled in the study. Serum ACE levels were determined photometrically with a kinetic test.

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Background: The burn wound represents a susceptible site for opportunistic colonization by organisms of endogenous and exogenous origin. Diminishing appetite is known to occur in patients with burn infection, yet its underlying reason is not fully understood. We have examined the levels of nesfatin 1, a protein that we consider to be a potential new treatment target for the solution of appetite and nutrition problem in patients with burn infection.

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Objective: Patients with chronic hepatitis C virus (HCV) infection may show a variety of rheumatic symptoms and signs. Anti-cyclic citrullinated peptide (anti-CCP) is widely used as as a marker, particularly for rheumatoid arthritis (RA), and may be positive in some diseases that also cause arthritis, such as systemic lupus erythematosus, familial Mediterranean fever, Behçet's disease, and psoriatic arthritis.

Materials And Methods: Blood samples were obtained (in routine protocols) from 57 patients with chronic HCV infection from the Gastroenterology Clinic of Ataturk University and Infectious Disease Clinic of Erzurum Region Research and Education Hospital.

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Bacillary Angiomatosis (BA) is frequently seen in patients with human immunodeficiency virus (HIV)-induced immunodeficiency. Our patient was a case that developed granuloma-like lesions in the area of a burn, 8 days after being burnt on the upper right arm by scalding water. No indication of immune deficiency was observed and no history of direct contact with cats was evident.

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Background: Alveolar echinococcosis (AE) is a potentially fatal and chronically progressive infestation produced by the multivesicular metacestode of Echinococcus multilocularis, which most commonly affects the liver, lungs, and brain.

Case Report: We present a case of AE in which an alveolar cyst, as a result of exophytic growth, adhered to intra-abdominal and pelvic organs and metastasized to the breast. Exploration showed that the exophytic cyst in the liver filled the entire abdominal cavity, reaching to the uterus and bladder, and was adherent to the neighboring tissues and organs.

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Background: We examine herein the demographic characteristics, implemented treatment methods, infection rates, and morbidities of patients with tandir burns from two burn centers.

Methods: In this study, gender, age, socioeconomic status, total body burn ratio, burn area, burn level, microorganisms isolated in burn wounds, implemented treatments, length of hospital stay, debridement and grafting operations, extremity amputations, and mortality among burn patients were investigated.

Results: Tandir burn patients were treated in the hospital for an average of 27.

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Background: The aim of this prospective study was therefore to evaluate the diagnostic value of preoperative serum High Mobility Group Box Protein-1 (HMGB-1) levels in patients with Acute Appendicitis (AA) who show normal white blood cell count (WBC) counts.

Method: Our study was carried out from October 2010 through November 2010 and included 20 healthy control group participants and 60 patients who presented at the emergency department of Erzurum Training and Research Hospital in Turkey with acute abdominal pain complaints, who were pathologically diagnosed with AA after laparotomy, and who agreed to participate in the study.

Results: Of the 60 patients who underwent appendectomies, 36 were male and 24 were female, and of the healthy group, 12 were male and 8 female.

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