Publications by authors named "Alban Cadu"
An atom-efficient synthesis of keto thioethers was devised via tandem gold/palladium catalysis. The reaction proceeds through a regioselective thiol attack at the β-position of the alcohol, followed by an alkyl, aryl, or benzyl 1,2-shift. Both acyclic and cyclic systems were studied, in the latter case leading to the ring expansion of cyclic substrates.
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- - Several chiral sulfonyl compounds were synthesized through an iridium-catalyzed asymmetric hydrogenation process.
- - The study examined various substitutions (vinylic, allylic, and homoallylic) and achieved high enantioselectivity across different olefin positions.
- - Notable stereoselectivity was observed for dialkyl substitutions, with bulkier Z-substrates hydrogenated more slowly and showing slightly lower enantioselectivity than E isomers.
Iridium, despite being one of the least abundant transition metals, has found several uses. N,P-ligated iridium catalysts are used to perform many highly selective reactions. These methodologies have been developed extensively over the past 15 years.
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