EMVC-2: an efficient single-nucleotide variant caller based on expectation maximization.

Motivation: Single-nucleotide variants (SNVs) are the most common type of genetic variation in the human genome. Accurate and efficient detection of SNVs from next-generation sequencing (NGS) data is essential for various applications in genomics and personalized medicine. However, SNV calling methods usually suffer from high computational complexity and limited accuracy.

Random-Walk Laplacian for Frequency Analysis in Periodic Graphs.

This paper presents the benefits of using the random-walk normalized Laplacian matrix as a graph-shift operator and defines the frequencies of a graph by the eigenvalues of this matrix. A criterion to order these frequencies is proposed based on the Euclidean distance between a graph signal and its shifted version with the transition matrix as shift operator. Further, the frequencies of a periodic graph built through the repeated concatenation of a basic graph are studied.

Counting malaria parasites with a two-stage EM based algorithm using crowsourced data.

Malaria eradication of the worldwide is currently one of the main WHO's global goals. In this work, we focus on the use of human-machine interaction strategies for low-cost fast reliable malaria diagnostic based on a crowdsourced approach. The addressed technical problem consists in detecting spots in images even under very harsh conditions when positive objects are very similar to some artifacts.