Publications by authors named "Alba N Lecona-Valera"
Article Synopsis
- The study investigates how using colistin in livestock, particularly in piglets, contributes to the rise of colistin-resistant bacteria.
- The researchers collected 175 colonies from pig feces and identified colistin resistance using various tests, finding that resistance was linked to specific plasmid-borne genes.
- Whole-genome sequencing revealed a diverse range of resistance and virulence genes, indicating that colistin resistance may develop through different acquisition pathways, presenting a risk for human health due to the potential spread of these resistant strains.
The heat shock protein family 70 (Hsp70) comprises chaperone proteins that play major multiple roles in Plasmodium asexual and sexual development. In this study, we analyzed the expression of Hsp70-1 in gametocytes, gametes, zygotes, and its participation in ookinete formation and their transition into oocysts. A monoclonal antibody against recombinant Hsp70-1 revealed its presence in zygotes and micronemes of ookinetes.
View Article and Find Full Text PDFBackground: Malaria parasites are transmitted by Anopheles mosquitoes. Although several studies have identified mosquito midgut surface proteins that are putatively important for Plasmodium ookinete invasion, only a few have characterized these protein targets and demonstrated transmission-blocking activity. Molecular information about these proteins is essential for the development of transmission-blocking vaccines (TBV).
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