Effects of early, late and self-selected time-restricted eating on visceral adipose tissue and cardiometabolic health in participants with overweight or obesity: a randomized controlled trial.

The optimal eating window for time-restricted eating (TRE) remains unclear, particularly its impact on visceral adipose tissue (VAT), which is associated with cardiometabolic morbidity and mortality. We investigated the effects of three TRE schedules (8 h windows in the early day, late day and participant-chosen times) combined with usual care (UC, based on education about the Mediterranean diet) versus UC alone over 12 weeks in adults with overweight or obesity. The primary outcome was VAT changes measured by magnetic resonance imaging.

Impact of lifestyle moderate-to-vigorous physical activity timing on glycemic control in sedentary adults with overweight/obesity and metabolic impairments.

Objective: Moderate-to-vigorous physical activity (MVPA) improves glucose levels; however, whether its timing affects daily glycemic control remains unclear. This study aims to investigate the impact of lifestyle MVPA timing on daily glycemic control in sedentary adults with overweight/obesity and metabolic impairments.

Methods: A total of 186 adults (50% women; age, 46.

Intermittent Hypoxic Training Increases and Prolongs Exercise Benefits in Adult Untrained Women.

Camacho-Cardenosa, Alba, Marta Camacho-Cardenosa, Johannes Burtscher, Pedro R. Olivares, Guillermo Olcina, and Javier Brazo-Sayavera. Intermittent hypoxic training increases and prolongs exercise benefits in adult untrained women.

Efficacy of different 8 h time-restricted eating schedules on visceral adipose tissue and cardiometabolic health: A study protocol.

Background And Aims: To investigate the efficacy and feasibility of three different 8 h time-restricted eating (TRE) schedules (i.e., early, late, and self-selected) compared to each other and to a usual-care (UC) intervention on visceral adipose tissue (VAT) and cardiometabolic health in men and women.

Mechanisms underlying the health benefits of intermittent hypoxia conditioning.

Intermittent hypoxia (IH) is commonly associated with pathological conditions, particularly obstructive sleep apnoea. However, IH is also increasingly used to enhance health and performance and is emerging as a potent non-pharmacological intervention against numerous diseases. Whether IH is detrimental or beneficial for health is largely determined by the intensity, duration, number and frequency of the hypoxic exposures and by the specific responses they engender.

Sex-specific dose-response effects of a 24-week supervised concurrent exercise intervention on cardiorespiratory fitness and muscular strength in young adults: The ACTIBATE randomized controlled trial.

Concurrent training has been postulated as an appropriate time-efficient strategy to improve physical fitness, yet whether the exercise-induced adaptations are similar in men and women is unknown. An unblinded randomized controlled trial was conducted to investigate sex-specific dose-response effects of a 24-week supervised concurrent exercise training program on cardiorespiratory fitness and muscular strength in young adults. One hundred and forty-four sedentary adults aged 18-25 years were assigned to either (i) a control group (n = 54), (ii) a moderate intensity exercise group (MOD-EX, n = 46), or (iii) a vigorous intensity exercise group (VIG-EX, n = 44) by unrestricted randomization.

Training zones through muscle oxygen saturation during a graded exercise test in cyclists and triathletes.

Use of muscle oxygen saturation (SmO) has been validated as a performance factor during incremental exercise with portable near-infrared stereoscopy (NIRS) technology. However, there is little knowledge about the use of SmO to identify training zones. The objective of this study was to evaluate the metabolic zones by SmO: maximum lipid oxidation zone (Fatmax), ventilatory thresholds (VT1 and VT2) and maximum aerobic power (MAP) during a graded exercise test (GXT).

Resistance circuit training combined with hypoxia stimulates bone system of older adults: A randomized trial.

Purpose: Aging leads to gradual irreversible decline in bone mass. As adherence to pharmacological treatment is poor, hypoxia combined with strength training has been suggested for therapeutic benefit for clinical populations. The present study investigated the effects of normobaric cyclic hypoxic exposure combined with resistance circuit training on bone of older adults.

Acute physiological response to a normobaric hypoxic exposure: sex differences.

Although preliminary studies suggested sex-related differences in physiological responses to altitude/hypoxia, controlled studies from standardised exposures to normobaric hypoxia are largely lacking. Hence, the goals of this study were to provide information on cardiorespiratory responses to a 7-h normobaric hypoxia exposure and to explore potential differences between men and women. In this crossover study, a total of 15 men and 14 women were subjected to a 7-h exposure in normoxia (FiO: 21%) and normobaric hypoxia (FiO: 15%).

Effect of hypoxic conditioning on functional fitness, balance and fear of falling in healthy older adults: a randomized controlled trial.

Background: Hypoxic conditioning has been proposed as a new tool to mitigate the sarcopenia and enhance health-related function, but decrements in standing balance have been observed during hypoxia exposure. The aim of the study was to evaluate the effect of a hypoxic conditioning training on functional fitness, balance and fear of falling in healthy older adults.

Methods: A total of 54 healthy older adults (aged 65-75 years), who voluntarily participated in the study, were randomly divided into three groups: the control group (CON), the normoxia training group (NT) that performed strength training in normoxia, and the hypoxia training group (HT) that trained under moderate hypoxic conditions at a simulated altitude of 2500 m asl.

Effects of moderate-intensity intermittent hypoxic training on health outcomes of patients recovered from COVID-19: the AEROBICOVID study protocol for a randomized controlled trial.

Background: Recent studies point to a lower number and reduced severity of cases in higher altitude cities with decreased oxygen concentration. Specific literature has shown several benefits of physical training, so, in this sense, physical training with hypoxic stimulus appears as an alternative that supports the conventional treatments of the COVID-19 patient's recovery. Thus, this study's primary aim is to analyze the effects of moderate-intensity intermittent hypoxic training on health outcomes in COVID-19 recovered patients.

Effect of intermittent hypoxic conditioning on inflammatory biomarkers in older adults.

Ageing is associated with chronic low-grade inflammation and with a decrease in muscle mass and strength. The aim of the study was to evaluate the effect of a resistance training programme in conditions of intermittent hypoxia on inflammatory biomarkers in older people. A total of 54 older adults (aged 65-75 years), who voluntarily participated in the study, were randomly divided into three groups: the control (CON) group, the resistance training normoxia (RTN) group that performed resistance training in normoxia and resistance training hypoxia (RTH) group that trained under hypoxic conditions at a simulated altitude of 2500 m above sea level.

Effects of 7-day intake of hydrogen-rich water on physical performance of trained and untrained subjects.

Hydrogen-rich water (HRW) is used as a supplement to improve performance and reduce fatigue in athletes. However, the potentially beneficial effects of HRW intake could be mediated by the training status of athletes. The purpose of the study was to analyse the ergogenic effect of intake of HRW for one week on aerobic and anaerobic performance, both in trained and untrained individuals.

Haematological responses to repeated sprints in hypoxia across different sporting modalities.

The aim was to determine the effects of repeated-sprint training in hypoxia on haematocrit and haemoglobin in different sporting modalities. Seventy-two participants were randomly allocated to Active-Repeated sprint in hypoxia (A-RSH, n= 8); Active-Repeated sprint in normoxia (A-RSN, n= 8); Active-Control (A-CON, n= 8); Team Sports-RSH (T-RSH, n= 8); Team Sports-RSN (T-RSN, n= 8); Team Sports-Control (T-CON, n= 8); Endurance-RSH (E-RSH, n= 8); Endurance-RSN (E-RSN, n= 8); Endurance-Control (E-CON, n= 8). Sessions consisted of two sets of five sprints of 10 swith recovery of 20 sbetween sprints and 10 min between sets.

Muscle Oxygen Desaturation and Re-Saturation Capacity Limits in Repeated Sprint Ability Performance in Women Soccer Players: A New Physiological Interpretation.

Muscle oxygen consumption could provide information on oxidative metabolism in women soccer players. Therefore, the objective of this study was to analyze muscle oxygenation dynamics during repeated sprint ability (RSA): (8 sprint × 20 s recovery) by near-infrared spectroscopy (NIRS). The sample was made up of 38 professional women soccer players.

Effects of normobaric cyclic hypoxia exposure on mesenchymal stem-cell differentiation-pilot study on bone parameters in elderly.

Background: Mesenchymal stem cells (MSC) of bone marrow are the progenitor of osteoblasts and adipocytes. MSC tend to differentiate into adipocytes, instead of osteoblasts, with aging. This favors the loss of bone mass and development of osteoporosis.

Effects of Swimming-Specific Repeated-Sprint Training in Hypoxia Training in Swimmers.

The aim of this study was to investigate the effect of a 4 weeks in-water swimming-specific repeated-sprint training in hypoxia (RSH) compared to similar training in normoxia (RSN). Following a repeated-measures, counterbalanced cross-over design, 10 swimmers were requested to perform two trials consisting of in-water repeated sprints in hypoxic (RSH, simulated 4,040 m; FiO = 13.7%) or normoxic (RSN, 459 m, FiO calibrated = 20.

Fatigue Increases in Resting Muscle Oxygen Consumption after a Women's Soccer Match.

Currently, near infrared spectroscopy has a clear potential to explain the mechanisms of fatigue by assessing muscle oxygenation. The objective of the study was to observe the changes in muscle oxygen consumption after an official women's soccer match. The sample was 14 players who competing in the second division of Spain of women's soccer.

Effects of strength training under hypoxic conditions on muscle performance, body composition and haematological variables.

The addition of a hypoxic stimulus during resistance training is suggested to increase the metabolic responses, enhancing hypertrophy and muscle strength. The purpose of this study was to investigate the effects of resistance training performed at submaximal intensities combined with normobaric hypoxia on muscular performance, body composition and haematological parameters. Thirty-two untrained subjects participated in this study (weight: 74.

Repeated sprint in hypoxia as a time-metabolic efficient strategy to improve physical fitness of obese women.

Purpose: To investigate the training and detraining effects of two different hypoxic high-intensity protocols on cardiorespiratory fitness, maximal fat oxidation and energy contribution in obese women.

Methods: 82 obese women completed a 12-week training of: (1) interval training in hypoxia (IHT; n = 19; 3 min at 90%W: 3 min at 55-65%W; FiO = 17.2%), (2) interval training in normoxia (INT; n = 20; 3 min at 90%W: 3 min at 55-65%W), (3) repeated sprint training in hypoxia (RSH; n = 22; 30 s at 130%W: 3 min at 55-65%W; FiO = 17.